DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ank and ankef1b

DIOPT Version :9

Sequence 1:NP_001162819.1 Gene:Ank / 43770 FlyBaseID:FBgn0011747 Length:1549 Species:Drosophila melanogaster
Sequence 2:XP_021322982.1 Gene:ankef1b / 100149106 ZFINID:ZDB-GENE-060810-68 Length:530 Species:Danio rerio


Alignment Length:651 Identity:140/651 - (21%)
Similarity:233/651 - (35%) Gaps:188/651 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 MALDNKNGIIKQNDATISFLRAARSGDIKKVMDFL-----DCGE--------------ISDINSC 69
            |||.:|          .:|...:.||  |.::.|.     ||.:              :..:..|
Zfish     1 MALASK----------ANFNNVSNSG--KPLLVFACEKAKDCEDLCINILEKGADPDAVDQVTRC 53

  Fly    70 NANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNV 134
                 :||..|:|.|.:.:...:.::|...:....:|..|.|.|:..|..:|:..|..|:|:..|
Zfish    54 -----SALMEASKAGALKLVRAISKKGGNPNLVDVEGRCAAHFAAEGGFLEVLQVLSAYSADFCV 113

  Fly   135 QSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGK 199
            .:.||.|||:.||....:.|||.|...|.||.|...:|..|..||...||              |
Zfish   114 STTNGNTPLHFAAAGGFNECCRFLSQRGCNPKLRNLEGQLPSQVAKSNGH--------------K 164

  Fly   200 VRLPALHIAAKKNDVNAAKLLLQHDPNADIVSKSGFTPLHIAAHYGNVDIATLLLNNKADVNYVA 264
            ..|..|..|.|::...:|...:  :||         .|..|..|                 ::..
Zfish   165 AALKELKKAEKRHVKFSAPDAI--NPN---------EPWAITLH-----------------DWSC 201

  Fly   265 KHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTK 329
            :|                           :||.|          ||     .:..::.|.|:.|.
Zfish   202 EH---------------------------EAALR----------RS-----FESAVELNKPVQTV 224

  Fly   330 TKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLL--LDY---- 388
            :.....:              ||..|:|||....:..:...|...|...:.:.:..  |.|    
Zfish   225 SLETFMS--------------LLSTNQAPVSNENLQRIIKQHDKNHKNVINLNEFFKGLKYLQKP 275

  Fly   389 -------------KANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVAS 440
                         :..|..:..|..|.|...|    :...||:.|.       .:||| |.::..
Zfish   276 FVISSYAPKPAKKEKGPKEKKRNKCTSLLPIC----MMPPELICKR-------EDSGL-PYYMIE 328

  Fly   441 FMGCINIVIYLLQHEASADLPTI--------------RGETPLHLAARANQADIIRI-LLRSAKV 490
            .  |   .:|......:.|.|:|              :..:.::...|:...:.:|: ..:...|
Zfish   329 I--C---QLYTHTKPFNRDQPSIHHIENDSAWYIEPEKIYSNINYCVRSGDLESLRLAFAQQVPV 388

  Fly   491 DAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAE 555
            |...:..:|||..|...||..:...|:..||::||.....::.||.|...|..:|:.:|:::||.
Zfish   389 DIKDQFYKTPLLTACSCGNYQVAEFLISLGADVNAVDQFSWTPLHHACHAGHVDIINMLVQSGAV 453

  Fly   556 NNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELL---LK 617
            .:||...|.|||..|.:..:.:.|:.|:..||::..:.|.....|.:|..|.|..||:|:   :|
Zfish   454 VDAVAMNGATPLMRAIESCRFSSVECLITAGANVMAENKQGQNCLDIAMIYGNARIVQLITSKVK 518

  Fly   618 N 618
            |
Zfish   519 N 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AnkNP_001162819.1 ANK 67..192 CDD:238125 38/124 (31%)
ANK repeat 72..103 CDD:293786 6/30 (20%)
Ank_2 77..167 CDD:289560 29/89 (33%)
ANK repeat 105..136 CDD:293786 10/30 (33%)
ANK repeat 138..169 CDD:293786 15/30 (50%)
ANK 204..320 CDD:238125 15/115 (13%)
ANK repeat 204..231 CDD:293786 6/26 (23%)
Ank_2 205..295 CDD:289560 10/89 (11%)
ANK repeat 233..264 CDD:293786 3/30 (10%)
ANK repeat 266..295 CDD:293786 1/28 (4%)
ANK 294..419 CDD:238125 25/143 (17%)
ANK repeat 299..330 CDD:293786 5/30 (17%)
Ank_4 300..353 CDD:290365 6/52 (12%)
ANK repeat 332..363 CDD:293786 6/30 (20%)
Ank_2 337..428 CDD:289560 18/109 (17%)
ANK 360..485 CDD:238125 23/158 (15%)
ANK repeat 365..395 CDD:293786 5/48 (10%)
ANK repeat 398..427 CDD:293786 7/28 (25%)
ANK repeat 431..462 CDD:293786 7/30 (23%)
Ank_2 436..526 CDD:289560 19/104 (18%)
ANK repeat 464..494 CDD:293786 4/30 (13%)
ANK 491..616 CDD:238125 39/127 (31%)
ANK repeat 496..527 CDD:293786 11/30 (37%)
Ank_2 501..592 CDD:289560 28/90 (31%)
ANK repeat 529..560 CDD:293786 9/30 (30%)
ANK 557..682 CDD:238125 21/65 (32%)
ANK repeat 562..590 CDD:293786 9/27 (33%)
Ank_5 582..636 CDD:290568 13/40 (33%)
ANK repeat 595..625 CDD:293786 9/27 (33%)
ANK repeat 628..657 CDD:293786
Ank_2 633..723 CDD:289560
ANK repeat 661..691 CDD:293786
ANK 692..812 CDD:238125
ANK repeat 693..724 CDD:293786
Ank_2 698..788 CDD:289560
ANK repeat 726..755 CDD:293786
ANK repeat 759..788 CDD:293786
ZU5 930..1034 CDD:128514
Death_ank 1439..1521 CDD:260029
ankef1bXP_021322982.1 ANK 10..137 CDD:238125 33/133 (25%)
ANK repeat 53..82 CDD:293786 7/33 (21%)
ANK repeat 84..115 CDD:293786 10/30 (33%)
ANK repeat 117..148 CDD:293786 15/30 (50%)
Ank_4 118..170 CDD:316185 22/65 (34%)
ANK 389..513 CDD:238125 38/123 (31%)
ANK repeat 397..425 CDD:293786 11/27 (41%)
ANK repeat 427..458 CDD:293786 9/30 (30%)
ANK repeat 460..491 CDD:293786 9/30 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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