Protein Alignment pan and SoxN

DIOPT Version :10

• Sequence 1: NP_726528.2
• Gene: pan / 43769
• FlyBaseID: FBgn0085432
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_001260269.1
• Gene: SoxN / 44275
• FlyBaseID: FBgn0029123
• Length: 761
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 134/646 - (20%)
• Similarity: 227/646 - (35%)
• Gaps: 193/646 - (29%)

  Fly   595 SNAIRGNVDNEITNQLKTSPSIRALPTENV--SHLITKTLS---------SANASLTAQELSITN 648
            |.|:.|:.         .||.....|..|:  |||....||         ||:.:.:.....:::
  Fly    23 SAALHGHA---------ASPYSALAPLMNLGQSHLTHSQLSHHNHHHHHMSAHIAASQSPNPLSS 78

  Fly   649 LFKERLCALQGN------AGSMKTEIFPMID----APYDLSIGSKTKHMNLEAKH---------- 693
            |.......|.|:      ....:.:..|:..    :|...||||  .||.....|
  Fly    79 LQSSMANTLNGSQVGQQQQQQQQQQSSPLHSSSELSPTQSSIGS--HHMTSPVSHQQHTQQQQHG 141

  Fly   694 --------------TSNAQSNESKETTNDKKKPH---IKKPLNAFMLYMKEMRAKVVAECTLKES 741
                          |..:.:|.:...|.:|.:.|   :|:|:||||::.:..|.|:.::.....:
  Fly   142 QQQHLGAGSALSSLTGGSSNNNNNSATANKNQQHADRVKRPMNAFMVWSRGQRRKMASDNPKMHN 206

  Fly   742 AAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNYGYVSKKKKRKKDRSTTDSG 806
            :.|::.||.:|.:||..|:..:.::|::.|.:||:.:|.:          |.:.|:|.::.|
  Fly   207 SEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEHPDY----------KYRPRRKTKTLT--- 258

  Fly   807 GNNMKKCRARFGLDQQSQWCKPCRRKKKCIRYMEALNGNGPAEDGSCFDEHGSQLSDDDEDDYDD 871
                 |.:.::.:..              :...:.:.|..|.|..:.....|        ....:
  Fly   259 -----KTKEKYPMGG--------------LMPGQTVGGGAPGEPVTPTRVQG--------QPGQN 296

  Fly   872 DKLGGSCGSADETNKIEDEDSESLNQSMPSPGCLSGLSSLQSPSTTMSLASPLNMNANSATNVIF 936
            ..|.||.|||..........::...|.|......:|    ..|:..|       |:|:
  Fly   297 QSLNGSGGSAAAAAAAAAAAAQQARQDMYQMNAPNG----YMPNGYM-------MHAD------- 343

  Fly   937 PASSNALLIVGADQPTAQQRPTLVSTSGSSSGSTSSIS---TTPNTSSTVSPVTCMTGPCLGSSQ 998
            ||.:.|.......|..|.||..:.....:......::|   |:|..||...|.:  ..|..|||.
  Fly   344 PAGAAAYQTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQQPGS--PSPYGGSSL 406

  Fly   999 ERAMMLGNRFSHLGMG----------LSPPVVSTSTSKSEPFFKPHPTVCNNPIFALPSIGNCSL 1053
            ::  ..|:...:.|.|          .||   |.|:.||||              ..||....:|
  Fly   407 QQ--QPGSPTPYGGGGGGGGQVSCQSHSP---SDSSIKSEP--------------VSPSPSAIAL 452

  Fly  1054 NISSMPNTSRNPIGANPRDINNPLSINQLTKRREYKNVELIEASESKTIVAHAATSIIQHVAVNG 1118
            |              |..:|||    |.:.| |||.:            .|.||.:.....|..|
  Fly   453 N--------------NNNNINN----NHIMK-REYSS------------AAAAAAAAAAAAAAGG 486

  Fly  1119 YHANHSLLNSNLGHL----HHQLNNRTENPN--RSEQTMLSVSNH--SVNSSECHKESDSQ 1171
            ...||.:   |:.||    .|.|:.:|::|:  :..|:|.....|  ..:.|:.|::...|
  Fly   487 GELNHLM---NMYHLPDEQRHLLHYQTDSPDLQQQHQSMQQQQQHLPQQHLSQQHQQIPQQ 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pan	NP_726528.2	HMG-box_TCF7-like	713..791	CDD:438812	21/80 (26%)
SoxN	NP_001260269.1	HMG-box_SoxB	177..252	CDD:438790	21/84 (25%)