Protein Alignment pan and Sox14

DIOPT Version :10

• Sequence 1: NP_726528.2
• Gene: pan / 43769
• FlyBaseID: FBgn0085432
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_476894.1
• Gene: Sox14 / 37822
• FlyBaseID: FBgn0005612
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 148/646 - (22%)
• Similarity: 229/646 - (35%)
• Gaps: 173/646 - (26%)

  Fly   518 TTQLPIVFNYNRESSAESIVTDPLLVPEFSTAPSTPSTGSNSGCSTGMVSGIFGLSQNRRKQRLA 582
            |...|......|...|....:.|..:|.||.:||..|:.|.:...|   .|    :|..:.|...
  Fly    28 TPARPATITIQRRHPAPKADSTPHTLPPFSPSPSPASSPSPAPAQT---PG----AQKTQSQAAI 85

  Fly   583 RHIETLTTNSFKSNAIRGNVDNEITNQLKTSPSIRALPTENVSHLITKTLSSANASLTAQELSIT 647
            .|...:.:.|....|              .:|.....|....:|..|.| .|.:.|...:|   :
  Fly    86 THPAAVASPSAPVAA--------------AAPKTPKTPEPRSTHTHTHT-HSQHFSPPPRE---S 132

  Fly   648 NLFKERLCALQGNAGSMKTEIFPMIDAPYDLSIGSKTKHMNLEAKHTSNAQSNESKETTNDKKKP 712
            .:..||   ...::|...|.....||:  .|..||        |:...|:.:..|..|...|..|
  Fly   133 EMDGER---SPSHSGHEMTLSMDGIDS--SLVFGS--------ARVPVNSSTPYSDATRTKKHSP 184

  Fly   713 -HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHELSREEQSKYYEKARQERQLHME 776
             |||:|:||||::.:..|.|:........:|.|::.|||||..||::::..|..:|.:.|:|||.
  Fly   185 GHIKRPMNAFMVWSQMERRKICERTPDLHNAEISKELGRRWQLLSKDDKQPYIIEAEKLRKLHMI 249

  Fly   777 LYPGWSARDNYGYVSKKKK-----------------------------------------RKKDR 800
            .||      ||.|..:||:                                         ||..|
  Fly   250 EYP------NYKYRPQKKQTRSPGSLKPNQDADGCEARNDTTNNNNSLTTLAINGTTTAGRKSKR 308

  Fly   801 ST-TDSGGNNMKKCRARFGLDQQSQWCKPCRRKKKCIRYMEALNGNG---PAEDGSCFDEHG--- 858
            || |...|:..|:.|...| |..|   ||....|  :...|.||...   |:.|.....:..
  Fly   309 STSTCQSGSASKRLRNDSG-DTSS---KPKYEVK--MESAEQLNSADIILPSADNLISYQSSEYL 367

  Fly   859 --SQLSDDDEDDYDDDKL-GGSCGSADETNKI----------EDEDSE----SL-----NQSMPS 901
              |.||:.|.|:....:| .|...|.:..:::          .:|||:    ||     |||.|:
  Fly   368 PLSTLSNADCDEKLHSELSSGPLESRENLSEVVNRFLPLFLGGNEDSQLGVSSLTQSQHNQSDPT 432

  Fly   902 PGCLSGLSSLQSPSTTMSLASPLN---------------MNAN-SATNVIFPASSNALLIVGADQ 950
            .|.:..:|.:          ||:|               :..| |:..:.....|::||....::
  Fly   433 AGLMDNISDI----------SPINDREELTEEVMRYLPYLEVNPSSDGLTLKVESSSLLGKPLNE 487

  Fly   951 PTAQQRPTLVSTSGSSSGSTSSISTTPNTSSTVSPVTCMTGPCLGSSQERAMMLGNRFSHLGMGL 1015
            |.......:|:.:...|.|.......|::..      |....|.|.|....:    .|.    .:
  Fly   488 PVFDSEDNIVNDANLHSASHQIPPYVPDSHD------CFAEDCGGDSSSHQV----EFE----VV 538

  Fly  1016 SPPVVSTSTSKSEPFFKP---HPTVCNNPIFALPSI---GNCSLNISSMPNTSRNP-IGAN 1069
            .|..|:.:.:.:.|:..|   |.|...:...|:||.   ..||:     ..||.:| ||.|
  Fly   539 RPQTVTMTMTCTLPYGGPDAGHTTFQADDFNAIPSAAEDSECSI-----LTTSNSPQIGFN 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pan	NP_726528.2	HMG-box_TCF7-like	713..791	CDD:438812	30/77 (39%)
Sox14	NP_476894.1	HMG-box_SoxC	186..261	CDD:438838	30/80 (38%)