Protein Alignment pan and lef1

DIOPT Version :9

• Sequence 1: NP_726528.2
• Gene: pan / 43769
• FlyBaseID: FBgn0085432
• Length: 1192
• Species: Drosophila melanogaster
• Sequence 2: NP_571501.1
• Gene: lef1 / 30701
• ZFINID: ZDB-GENE-990714-26
• Length: 365
• Species: Danio rerio
• Alignment Length: 461
• Identity: 141/461 - (30%)
• Similarity: 196/461 - (42%)
• Gaps: 145/461 - (31%)

  Fly   378 SNESILPQKTNA------VHSKIPDVESESDFFLTSAKPKTLVEIEDIIL---QLASSVNMHQSS 433
            :.:.::|.|...      :.::|...|.|.|          |.||:..::   :::.:.|.|.::
Zfish    17 ATDEMIPFKDEGDPHKEQIFAEISHSEEEGD----------LAEIKSSLVNETEISPNSNSHDAA 71

  Fly   434 SAS--TP---HESYSDSVKSDCEESNSAPTCIWHSTRQTFRHKKDVEPCSTAAEIILEYASLSSS 493
            ..|  ||   ||.:.|                         |..|.           :...|.|.
Zfish    72 RQSQITPDSYHEKHRD-------------------------HPDDG-----------KLQDLYSK 100

  Fly   494 SNIETSR----LLTSASNLTDVTENY--NVTTQLPIVFNYNRESSAESIVTDPLLVPEFSTAPST 552
            .:...|.    ::|:.:|     |.|  |.:...||....|:.         |::.|..:..|.|
Zfish   101 GHPYPSYPGYIMMTNMNN-----EPYMNNGSLSPPIPRTSNKV---------PVVQPSHAVHPLT 151

  Fly   553 P-STGSNSGCSTGMVSGIFGLSQNRRKQRLARHIETLTTNSFKSNAIRGNVDNEITNQLKTSPSI 616
            | .|.|:...:.|..||......|.::..:.||                :...:|.|....||.
Zfish   152 PLITYSDEHFAPGPHSGHHPQDVNPKQAGMPRH----------------HPGPDIPNFYPLSPG- 199

  Fly   617 RALPTENVSHLITKTLSSANASLTAQELSITNLFKERLCALQGNAGSMKTEI------FPMIDAP 675
                  .|..: |..|               ..|...:  :.|..|...|.|      .|.:...
Zfish   200 ------GVGQM-TPPL---------------GWFSHHM--VPGPPGPHATGIPHPAIVNPQVKQE 240

  Fly   676 YDLSIGSKTKHMNLEAKHTSNAQSNESKETTNDKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKE 740
            :|      |..|:::.:|      .:.||  .:.|:|||||||||||||||||||.|||||||||
Zfish   241 HD------TDLMHMKPQH------EQRKE--QEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKE 291

  Fly   741 SAAINQILGRRWHELSREEQSKYYEKARQERQLHMELYPGWSARDNYGYVSKKKKRKKDRSTTDS 805
            |||||||||||||.||||||:||||.||:||||||:||||||||||||   ||||||:::....:
Zfish   292 SAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYG---KKKKRKREKIQEPA 353

  Fly   806 GGNNMK 811
            .|...:
Zfish   354 SGTGQR 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pan	NP_726528.2	SOX-TCF_HMG-box	713..784	CDD:238684	64/70 (91%)
lef1	NP_571501.1	CTNNB1_binding	1..210	CDD:285538	50/291 (17%)
		SOX-TCF_HMG-box	264..335	CDD:238684	64/70 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	134	1.000	Domainoid score	I4951
eggNOG	1	0.900	-	-		E1_KOG3248
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000839
OrthoInspector	1	1.000	-	-		otm25294
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10373
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2732
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.990