DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS3A and RPS1B

DIOPT Version :9

Sequence 1:	NP_001245404.1	Gene:	RpS3A / 43768	FlyBaseID:	FBgn0017545	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_013648.1	Gene:	RPS1B / 854939	SGDID:	S000004528	Length:	255	Species:	Saccharomyces cerevisiae

Alignment Length:	268	Identity:	141/268 - (52%)
Similarity:	186/268 - (69%)	Gaps:	13/268 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGR 65
            |||||||.||: ||||.||||||||:||:|:|:|||:.|:.|.:||||||::.|.:.|||.||||
Yeast     1 MAVGKNKRLSR-GKKGLKKKVVDPFTRKEWFDIKAPSTFENRNVGKTLVNKSTGLKNASDALKGR 64

  Fly    66 VFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEA 130
            |.||.|||||...|  .||||.:|..::||.:|:|.||||||.||||.||||:||||||||.|..
Yeast    65 VVEVCLADLQGSED--HSFRKVKLRVDEVQGKNLLTNFHGMDFTTDKLRSMVRKWQTLIEANVTV 127

  Fly   131 KTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDS 195
            ||.|.|:||:|.|.||.|.....::..|||.|.:|.||..:::|:|.||..:.|.||.:||..:.
Yeast   128 KTSDDYVLRIFAIAFTRKQANQVKRHSYAQSSHIRAIRKVISEILTREVQNSTLAQLTSKLIPEV 192

  Fly   196 IAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGY 260
            |.|:||.:.:.|:||.::::||||:||:|:|||..|:.|||:|.|:.....||          |:
Yeast   193 INKEIENATKDIFPLQNIHVRKVKLLKQPKFDVGALMALHGEGSGEEKGKKVS----------GF 247

  Fly   261 EPPVQEAV 268
            :..|.|.|
Yeast   248 KDEVLETV 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS3A	NP_001245404.1	Ribosomal_S3Ae	21..224	CDD:395802	109/202 (54%)
RPS1B	NP_013648.1	Ribosomal_S3Ae	22..221	CDD:395802	107/200 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	230	1.000	Domainoid score	I410
eggNOG	1	0.900	-	-		E1_COG1890
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68112
Inparanoid	1	1.050	270	1.000	Inparanoid score	I603
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62242
OrthoFinder	1	1.000	-	-		FOG0002587
OrthoInspector	1	1.000	-	-		otm46672
orthoMCL	1	0.900	-	-		OOG6_100723
Panther	1	1.100	-	-	LDO	PTHR11830
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2271
SonicParanoid	1	1.000	-	-		X1698
TreeFam	1	0.960	-	-
	14	13.860