DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS3A and rps3a

DIOPT Version :9

Sequence 1:	NP_001245404.1	Gene:	RpS3A / 43768	FlyBaseID:	FBgn0017545	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001008075.1	Gene:	rps3a / 493437	XenbaseID:	XB-GENE-976731	Length:	264	Species:	Xenopus tropicalis

Alignment Length:	268	Identity:	183/268 - (68%)
Similarity:	213/268 - (79%)	Gaps:	4/268 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAVGKNKGLSKGGKKGGKKKVVDPFSRKDWYDVKAPNMFQTRQIGKTLVNRTQGQRIASDYLKGR 65
            |||||||.|:||||||.|||:|||||:|||||||||.||..|.:|||||.||||.:||||.||||
Frog     1 MAVGKNKRLTKGGKKGAKKKIVDPFSKKDWYDVKAPAMFNIRNLGKTLVTRTQGTKIASDGLKGR 65

  Fly    66 VFEVSLADLQKDIDPERSFRKFRLIAEDVQDRNVLCNFHGMDLTTDKYRSMVKKWQTLIEAIVEA 130
            ||||||||||.|   |.:||||:||.||||.:|.|.||||||||.||..||||||||:|||.|:.
Frog    66 VFEVSLADLQND---EVAFRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDV 127

  Fly   131 KTVDGYLLRVFCIGFTAKDQQSQRKTCYAQQSQVRKIRARMTDIITNEVSGADLKQLVNKLALDS 195
            ||.||||||:||:|||.|.....|||.|||..|||:||.:|.:|:|.||...|||::||||..||
Frog   128 KTTDGYLLRLFCVGFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDS 192

  Fly   196 IAKDIEKSCQRIYPLHDVYIRKVKVLKKPRFDVSKLLELHGDGGGKSVEAVVSSEGAVIDRPEGY 260
            |.|||||:||.||||||||:||||:||||:|::.||:||||:|||....| ....||.::|.:||
Frog   193 IGKDIEKACQSIYPLHDVYVRKVKMLKKPKFELGKLMELHGEGGGAGKPA-GDETGAKVERADGY 256

  Fly   261 EPPVQEAV 268
            ||||||:|
Frog   257 EPPVQESV 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS3A	NP_001245404.1	Ribosomal_S3Ae	21..224	CDD:395802	141/202 (70%)
rps3a	NP_001008075.1	Ribosomal_S3Ae	21..221	CDD:376434	141/202 (70%)
rps3a	NP_001008075.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..264		16/31 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	293	1.000	Domainoid score	I1487
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68112
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2129
OMA	1	1.010	-	-		QHG62242
OrthoDB	1	1.010	-	-		D1207239at2759
OrthoFinder	1	1.000	-	-		FOG0002587
OrthoInspector	1	1.000	-	-		oto103027
Panther	1	1.100	-	-	LDO	PTHR11830
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2271
SonicParanoid	1	1.000	-	-		X1698
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.110