DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ci and ELF6

DIOPT Version :9

Sequence 1:	NP_524617.3	Gene:	ci / 43767	FlyBaseID:	FBgn0004859	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_196044.2	Gene:	ELF6 / 830303	AraportID:	AT5G04240	Length:	1340	Species:	Arabidopsis thaliana

Alignment Length:	628	Identity:	135/628 - (21%)
Similarity:	210/628 - (33%)	Gaps:	187/628 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 RTNSASSFHDPYVNCASAFHLAGLGLGSADFLGSRGLSSLGELHNAAVAAAAAGSLASTDFHFSV 191
            |.||      |......|..|.||...::..|....:..|.....:....::..|....: |..|
plant   746 RKNS------PTKKIQHALSLGGLFSDTSQMLDFTTIRWLQRKSRSKAKPSSTSSFTPCE-HLEV 803

  Fly   192 --DGNRRLGSPRPPGGSIRASI--SRKRALSSSP------------YSDSFDINSMIRFSPNS-- 238
              ||..|.......|......|  |||:.|:..|            .|..|| .:...||..|
plant   804 KADGKLRDNLDSQTGKKEEKIIQYSRKKKLNPKPSAEQVQELATLAKSKDFD-KTCKNFSSRSHL 867

  Fly   239 ---LATIMNGSRGSS-------------AASGSYGH--------------ISATALNPMSHVH-- 271
               :.:.||...|.|             ::|.:.||              :.....|.:|.|:
plant   868 DSAIRSEMNSEIGDSGRVIGVSFSINPCSSSFTVGHGQEHPEITVKFGSDLDGNVTNSLSMVNGD 932

  Fly   272 -------STRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVN--DVHP---NLS 324
                   |...:|.|.|.:.::....|         ||   .|:..|.::.|:  |.|.   .||
plant   933 SADLTLTSISREQHQGHSMTSNNNGSN---------SG---SHVVASQTILVSTGDNHDGPRKLS 985

  Fly   325 DSHIQITTSPTVTKDVSQVPAAAF-----SLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVEAD 384
            ..::....|....::..::....|     ::.|::|.::.    :.|.|.|..:..|...|||..
plant   986 GDYVCSDVSVRGIQEAVEMSDQEFGEPRSTVTNIEDEQQS----QIVKPTQREAVFGDHEQVEGA 1046

  Fly   385 SASSQLSDRC------------------------YNNVVNNIT--GIP---GDVKVNSRLDEYIN 420
            .|.|...:.|                        ..|:|.::|  |.|   .|:..:|..||..:
plant  1047 EAVSTRENLCSEIILHTEHSSAHVGMEIPDINTASENLVVDMTHDGEPLESSDILSSSNGDEASS 1111

  Fly   421 CGSISIP---SNEYDCANADTTDIKDEPGDF------------IETNCHWRSCRIEFI------- 463
            .|...:.   |.|.:.::::.|::.:.|...            .|||.:..| .|.||
plant  1112 NGLQVLNDELSMESEVSSSENTEVIEAPNSMGEAKKKRKIESESETNDNPES-SIGFIRSPCEGL 1175

  Fly   464 ------------------TQDELVKHI--------------NNDHIQTNKKAFVCRWEDCTRGEK 496
                              |.||..|.|              ....:.|......|..|.|   :.
plant  1176 RSRGKRKATCETSLKHTETSDEEKKPIAKRLKKTPKACSGSRQQEVPTTTHPNRCYLEGC---KM 1237

  Fly   497 PFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNA 561
            .|:::..|..|.|       ::||.|||.|.:...:.|..|.|.|..|:|:.|.:.|||..|...
plant  1238 TFESKAKLQTHKR-------NRCTHEGCGKKFRAHKYLVLHQRVHKDERPFECSWKGCSMTFKWQ 1295

  Fly   562 SDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKH-VKTVH 603
            ..|.:|. |.|:.|:|||||..||...:...|...:| .||:|
plant  1296 WARTEHL-RLHTGERPYICKVDGCGLSFRFVSDYSRHRRKTMH 1337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..530	CDD:290200	9/26 (35%)
		C2H2 Zn finger	519..541	CDD:275368	9/21 (43%)
		zf-H2C2_2	533..560	CDD:290200	11/26 (42%)
		C2H2 Zn finger	549..572	CDD:275368	8/22 (36%)
		C2H2 Zn finger	580..601	CDD:275368	6/21 (29%)
ELF6	NP_196044.2	JmjN	17..50	CDD:396793
		JmjC	292..411	CDD:396791
		C2H2 Zn finger	1230..1255	CDD:275368	8/34 (24%)
		C2H2 Zn finger	1253..1275	CDD:275368	9/21 (43%)
		C2H2 Zn finger	1283..1305	CDD:275368	8/22 (36%)
		C2H2 Zn finger	1313..1333	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000