Protein Alignment ci and zic4

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001070080.3
• Gene: zic4 / 767673
• ZFINID: ZDB-GENE-040622-4
• Length: 530
• Species: Danio rerio
• Alignment Length: 570
• Identity: 148/570 - (25%)
• Similarity: 223/570 - (39%)
• Gaps: 175/570 - (30%)

  Fly    72 IQPQICNENT---LLGNAG-----HQHNHQPQHVHNINVTGQPHDFHPAYRIPGYMEQLYSLQRT 128
            :.|.....||   |:..||     |.|:|.||     :|||          .||:....:|:..:
Zfish    11 MDPAFSKRNTTLRLVDLAGAHHHHHHHHHTPQ-----SVTG----------FPGFSSHPHSMAHS 60

  Fly   129 NSASSFHDPYVNCASAFHLAGLGLGSADFLGSRGLSSLGELHNAAVAAAAAGSLASTDFHFS--V 191
            :......:|             .||.:.|    |...:|  |:||:..:..........|.:  :
Zfish    61 HPGEMTAEP-------------RLGPSPF----GPEHMG--HSAALKISPTHHYPHHHHHHNHHI 106

  Fly   192 DGNRRLGSPRPPG-GSIRASISRKRALSSSPYSDSFDINS-------MIR--FSPNSLATIMNGS 246
            .|:..:.|.:... |.::|        ::.|||.|....:       :||  .:..::..:.:.:
Zfish   107 AGHSEVVSSQTGAFGPVQA--------ATVPYSMSHTAQALSAGRDFLIRRDLTAQAMPVLTDQT 163

  Fly   247 RGSSAASGSYGHISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTS 311
            .||::..|.:  :|.|...|..:.|
Zfish   164 SGSASHHGMF--VSTTGSYPGHYGH---------------------------------------- 186

  Fly   312 ASLRVNDVHPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPEQPSSTSG 376
                    ||: ..:|   |..|.:..|.....|......|        |..:..:|.:
Zfish   187 --------HPD-PGNH---TLFPGLHHDQPSTGAPGGQALN--------GQIRLGIPAE------ 225

  Fly   377 GVAQVEADSASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYINCGSISIPSNEYDCANADTTDI 441
              ..|.:|..|...|.|......:.:.|. |.:.:|..|..:.:.|:
Zfish   226 --MYVRSDHLSQVASSRADPFAASPLHGY-GGLNLNMNLSAHHHHGA------------------ 269

  Fly   442 KDEPGDFI---------ETNCHW--------RSCRIEFITQDELVKHINNDHIQTNKKA-FVCRW 488
                |.|.         |..|.|        :.|...:.|..|||.|:..:|:...::| .:|.|
Zfish   270 ----GAFFRYMRQPIKQELICKWLEPEHSAKKLCSKTYSTMHELVTHVTVEHVGGPEQANHICFW 330

  Fly   489 EDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPG 553
            |:|.|..|||||:|.||.|:|.||||||..|.|.||.|.::|.||||.|.|:||||||:.||:.|
Zfish   331 EECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDG 395

  Fly   554 CSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVH 603
            |.:.|:|:|||.|| :..|:::|||.||..||.|.||.|||||||:| ||
Zfish   396 CDRRFANSSDRKKH-SHVHTSDKPYNCKVRGCDKSYTHPSSLRKHMK-VH 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	11/17 (65%)
		SFP1	<513..603	CDD:227516	52/89 (58%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	16/26 (62%)
		C2H2 Zn finger	549..572	CDD:275368	11/22 (50%)
		C2H2 Zn finger	580..601	CDD:275368	14/20 (70%)
zic4	NP_001070080.3	None