Protein Alignment ci and YY1

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_003394.1
• Gene: YY1 / 7528
• HGNCID: 12856
• Length: 414
• Species: Homo sapiens
• Alignment Length: 81
• Identity: 17/81 - (20%)
• Similarity: 31/81 - (38%)
• Gaps: 19/81 - (23%)

  Fly   102 WTDDPEKMLNVQELDGIWFLIVAGFLECYFGYSVVFGIMGVVTERV--IASLLIDNYEKNTNILI 164
            |...|..:|.:.:|.. |.|...|.|:              :.|.:  ...|::.:..:||...|
Human    72 WKTLPSSLLKLNQLQE-WQLHRTGLLK--------------IPEFIGRFQHLIVLDLSRNTISEI 121

  Fly   165 P--VAIITMSQFFAIS 178
            |  :.::|..|...:|
Human   122 PRGIGLLTRLQELILS 137

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886
		SFP1	<513..603	CDD:227516
		C2H2 Zn finger	519..541	CDD:275368
		zf-H2C2_2	533..560	CDD:463886
		C2H2 Zn finger	549..572	CDD:275368
		C2H2 Zn finger	580..601	CDD:275368
YY1	NP_003394.1	Interaction with the SMAD1/SMAD4 complex. /evidence=ECO:0000269|PubMed:15329343	1..170		17/81 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..81		2/8 (25%)
		Gly-rich region involved in interaction with HCFC1. /evidence=ECO:0000269|PubMed:20805357	116..260		7/22 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..203
		Involved in nuclear matrix association. /evidence=ECO:0000269|PubMed:9493912	257..341
		COG5048	<268..407	CDD:227381
		Binding to DNA. /evidence=ECO:0000269|PubMed:18950698	295..414
		C2H2 Zn finger	298..320	CDD:275368
		C2H2 Zn finger	327..347	CDD:275368
		Involved in repression of activated transcription	333..371
		C2H2 Zn finger	355..377	CDD:275368
		Involved in masking transactivation domain	371..397
		C2H2 Zn finger	385..407	CDD:275368