Protein Alignment ci and Zic1

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_073168.1
• Gene: Zic1 / 64618
• RGDID: 620110
• Length: 447
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 163/602 - (27%)
• Similarity: 226/602 - (37%)
• Gaps: 223/602 - (37%)

  Fly   142 ASAFHLAG------LGLGSADFLGSRGLSSLGELHNAAVAAAAAGSLASTDFHFSVDGNRRLGSP 200
            ||..|.||      :|||...|....|..   :|:.::...|:||..|.|.
  Rat    19 ASRHHSAGDVAERDVGLGINPFADGMGAF---KLNPSSHELASAGQTAFTS-------------- 66

  Fly   201 RPPGGSIRASISRKR------ALSSSPYSDSFDINSMIRFSPNSLATIMNGSRGSSAASGSYGHI 259
            :.||.:..|::....      :.||:.::.:.|.            ...|...|.:||:.|..|
  Rat    67 QAPGYAAAAALGHHHHPGHVGSYSSAAFNSTRDF------------LFRNRGFGDAAAAASAQH- 118

  Fly   260 SATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVNDVHPNLS 324
                                 .|..||||             ||...|..|.|:
  Rat   119 ---------------------SLFAASAG-------------GFGGPHGHTDAA----------- 138

  Fly   325 DSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVEADSASSQ 389
             .|:                  .||                           |:.:..|..||.
  Rat   139 -GHL------------------LFS---------------------------GLHEQAAGHASP- 156

  Fly   390 LSDRCYNNVVNN--ITGIPGDVKVNSRLDEYINCGSISIPSNEYDCA---------NADTTDIKD 443
                   ||||.  ..|..||  :..|.::|   |.::.|.:|:..|         |.:.. ...
  Rat   157 -------NVVNGQMRLGFSGD--MYPRPEQY---GQVTSPRSEHYAAPQLHGYGPMNVNMA-AHH 208

  Fly   444 EPGDFI---------ETNCHW----------RSCRIEFITQDELVKHINNDHI----QTNKKAFV 485
            ..|.|.         |..|.|          :||...|.|..|||.|:..:|:    |:|   .:
  Rat   209 GAGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSN---HI 270

  Fly   486 CRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCE 550
            |.||:|.|..|||||:|.||.|:|.||||||..|.|.||.|.::|.||||.|.|:||||||:.||
  Rat   271 CFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCE 335

  Fly   551 YPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKG 615
            :.||.:.|:|:|||.||.: .|:::|||:||.  |.|.||.|||||||:| ||.:....::
  Rat   336 FEGCDRRFANSSDRKKHMH-VHTSDKPYLCKM--CDKSYTHPSSLRKHMK-VHESSSQGSQ---- 392

  Fly   616 LPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSNHHLVNGVRA 680
             |...|:|..:             .|:|.:..|..     |.:|:..|.|..||:.||
  Rat   393 -PSPAASSGYE-------------SSTPPTIVSPT-----TDNPTTSSMSPSSSAVHH------- 431

  Fly   681 SDSLLTYSPDDLAENLN 697
                 |.....|:.|.|
  Rat   432 -----TAGHSALSSNFN 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	11/17 (65%)
		SFP1	<513..603	CDD:227516	51/89 (57%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	16/26 (62%)
		C2H2 Zn finger	549..572	CDD:275368	11/22 (50%)
		C2H2 Zn finger	580..601	CDD:275368	13/20 (65%)
Zic1	NP_073168.1	zf_ZIC	219..264	CDD:436441	12/44 (27%)
		C2H2 Zn finger	276..296	CDD:275368	12/19 (63%)
		SFP1	<298..382	CDD:227516	50/86 (58%)
		C2H2 Zn finger	304..326	CDD:275368	12/21 (57%)
		C2H2 Zn finger	334..356	CDD:275368	11/22 (50%)
		C2H2 Zn finger	364..384	CDD:275368	14/22 (64%)