Protein Alignment ci and zic2

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001017025.2
• Gene: zic2 / 549779
• XenbaseID: XB-GENE-482654
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 614
• Identity: 162/614 - (26%)
• Similarity: 225/614 - (36%)
• Gaps: 229/614 - (37%)

  Fly   170 HNAAVAAAAAG---------SLASTDF----HFSV-------------DGNRRLGSPRPPGGSIR 208
            |:||||||||.         |||...|    |...             .|....|...|.||
 Frog    27 HHAAVAAAAAAAAEMQERELSLAQNSFVEPTHMGAFKLNPGGGSGGGSGGGSGGGGGGPVGG--- 88

  Fly   209 ASISRKRALSSSPYSDSFDINSMIRFSPNSLA-------TIMNGSR-----------GSSAA-SG 254
            |..|....||....:.:|  .|...:..::||       ...|..|           |::|| .|
 Frog    89 AGASGPHDLSPPGQTSAF--TSQAGYPASALAPHAAYTGAAFNSPRDFLFRGRGFAEGTAAAGGG 151

  Fly   255 SYGHISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVNDV 319
            .:|.....|.:...|.|..:|...: |             ||         ||:          :
 Frog   152 QHGLFGPPAGSLHHHPHHHQLSHGE-H-------------PQ---------GHI----------L 183

  Fly   320 HPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVEAD 384
            .|.:.|.|                 |||                       ..:..||..::
 Frog   184 FPGIHDQH-----------------AAA-----------------------SQNALGGQMRL--- 205

  Fly   385 SASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYINCGSISIP----------SNEYDCANADTT 439
                               |:||:  :..|.::|   ..:|.|          .|:|...|....
 Frog   206 -------------------GLPGE--MFGRTEQY---RQVSSPRGDPYTAAQLHNQYAPMNMGMN 246

  Fly   440 -------DIKDEPGDFI----------ETNCHW----------RSCRIEFITQDELVKHINNDHI 477
                   .....||.|.          |..|.|          :||...|.|..|||.|::.:|:
 Frog   247 MAAHHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHELVTHVSVEHV 311

  Fly   478 ----QTNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHL 538
                |:|   .:|.||:|:|..|||||:|.||.|:|.||||||..|.|.||.|.::|.||||.|.
 Frog   312 GGPEQSN---HICFWEECSREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHK 373

  Fly   539 RSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVH 603
            |:||||||:.||:.||.:.|:|:|||.||.: .|:::|||:||.  |.|.||.|||||||:|.
 Frog   374 RTHTGEKPFQCEFEGCDRRFANSSDRKKHMH-VHTSDKPYLCKM--CDKSYTHPSSLRKHMKV-- 433

  Fly   604 GAEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDIS 668
                     |:..|....:|....:....:.....:  ||.||         |.:|::...:...
 Frog   434 ---------HESSPQGSESSPAASSGYESSTPPGLV--SPNSE---------TQNPNLSPAAAAV 478

  Fly   669 SSNHHLVNGVRASDSLLTYSPDDLAENLN 697
            |:.|.:.:|...:          ||.|.|
 Frog   479 SAVHSVSSGASGA----------LASNFN 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	11/17 (65%)
		SFP1	<513..603	CDD:227516	51/89 (57%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	16/26 (62%)
		C2H2 Zn finger	549..572	CDD:275368	11/22 (50%)
		C2H2 Zn finger	580..601	CDD:275368	13/20 (65%)
zic2	NP_001017025.2	zf_ZIC	269..314	CDD:436441	12/44 (27%)
		COG5048	<284..438	CDD:227381	80/170 (47%)
		C2H2 Zn finger	324..346	CDD:275368	13/21 (62%)
		C2H2 Zn finger	354..376	CDD:275368	12/21 (57%)
		C2H2 Zn finger	384..406	CDD:275368	11/22 (50%)
		C2H2 Zn finger	414..434	CDD:275368	14/32 (44%)