Protein Alignment ci and zic3

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001005691.1
• Gene: zic3 / 448197
• XenbaseID: XB-GENE-480431
• Length: 441
• Species: Xenopus tropicalis
• Alignment Length: 458
• Identity: 142/458 - (31%)
• Similarity: 196/458 - (42%)
• Gaps: 155/458 - (33%)

  Fly   258 HISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGF--SIGHMPTSASLRVNDVH 320
            |.:|..|:|.||..|:.         ::||     .|||   |||:  |:||
 Frog    44 HAAAFKLSPASHDLSSS---------QSSA-----FTPQ---ASGYANSLGH------------- 78

  Fly   321 PNLSDSHIQITTSPTVTKDVSQVPA---AAFSLKNLDDAREKKGPFKDVVPEQPSSTSGGVAQVE 382
                              ...|||:   |||:.......|.:.....|      |:::||...:.
 Frog    79 ------------------HAGQVPSYGGAAFNSTRDFLFRNRNSGIAD------STSAGGQHGLF 119

  Fly   383 A--------------------DSASSQLSDRCYNNVVNN--ITGIPGDVKVNSRLDEYINCGSIS 425
            |                    :.:||..|..  .:|||.  ..|:.||  :..|.|.|     .:
 Frog   120 ASHGPPGIGEPPGHLIFPGLHEQSSSHTSSN--GHVVNGQMHLGLRGD--IFGRPDPY-----RA 175

  Fly   426 IPS-----------NEYDCANAD-TTDIKDEPGDFI---------ETNCHW----------RSCR 459
            :||           :.|:..|.. .......||.|.         |.:|.|          ::|.
 Frog   176 VPSPRTDHYAAAQFHNYNHMNMSMNVAAHHGPGAFFRYMRQPIKQELSCKWLEESPMNRPQKTCD 240

  Fly   460 IEFITQDELVKHINNDHI----QTNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCT 520
            ..|.:..|||.|:..:|:    |||   .:|.||:|.||.|.|||:|.||.|:|.||||||..|.
 Frog   241 RTFSSMHELVTHMTMEHVGGPEQTN---HICYWEECPRGGKSFKAKYKLVNHIRVHTGEKPFPCP 302

  Fly   521 FEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGC 585
            |.||.|.::|.||||.|.|:||||||:.||:.||.:.|:|:|||.||.: .|:::||||||.  |
 Frog   303 FPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMH-VHTSDKPYICKV--C 364

  Fly   586 TKRYTDPSSLRKHVKTVHGAE--------------------FYANKKHKGLPLNDANSRLQQNNS 630
            .|.||.|||||||:| ||.::                    ..||.:.   |..::::..|.|||
 Frog   365 DKSYTHPSSLRKHMK-VHESQGSDSSPAASSGYESATPPAMVSANSEE---PSKNSSATHQTNNS 425

  Fly   631 RHN 633
            .||
 Frog   426 SHN 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	11/17 (65%)
		SFP1	<513..603	CDD:227516	52/89 (58%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	16/26 (62%)
		C2H2 Zn finger	549..572	CDD:275368	11/22 (50%)
		C2H2 Zn finger	580..601	CDD:275368	13/20 (65%)
zic3	NP_001005691.1	zf_ZIC	216..261	CDD:436441	10/44 (23%)
		C2H2 Zn finger	273..293	CDD:275368	12/19 (63%)
		SFP1	<295..379	CDD:227516	51/86 (59%)
		C2H2 Zn finger	301..323	CDD:275368	12/21 (57%)
		C2H2 Zn finger	331..353	CDD:275368	11/22 (50%)
		C2H2 Zn finger	361..381	CDD:275368	14/22 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	375..441		15/58 (26%)