DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ci and sug

DIOPT Version :9

Sequence 1:	NP_524617.3	Gene:	ci / 43767	FlyBaseID:	FBgn0004859	Length:	1397	Species:	Drosophila melanogaster
Sequence 2:	NP_610826.1	Gene:	sug / 36424	FlyBaseID:	FBgn0033782	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	121/338 - (35%)
Similarity:	160/338 - (47%)	Gaps:	70/338 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 PFKDVVPEQPSSTSGGVAQVEA--DSASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYINCGSI 424
            |...:.|.:|.:..|...:.::  ..|..|..:.|.:.|     ..|.|.|         :|.|.
  Fly    69 PTPPITPPRPIAGYGYRQRTQSVIMKARGQQDELCRSPV-----EFPDDSK---------SCSSS 119

  Fly   425 SIPSNEYDCANADTTDIKDEPGDFIETNCHWRSCRIEFITQDELVKHINNDH--IQTNKKAFVCR 487
            |      :|..|         .||:   |:|..|...|.|.|.|.:|:...|  .......:.||
  Fly   120 S------ECGTA---------SDFV---CNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCR 166

  Fly   488 WEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYP 552
            |..|.|.|:.|.|:|.::||.|.||.||||:|..  |.|::||.||||.|:|||:|||||.|.:.
  Fly   167 WRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKIHIRSHSGEKPYKCSFE 229

  Fly   553 GCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTV-HGAEFYANKKHKGL 616
            ||.||:||:|||.|| .||||.||||:||..||.|||||||||||||||. |.....|::
  Fly   230 GCQKAYSNSSDRFKH-TRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQ----- 288

  Fly   617 PLNDANSRLQQNNSRHNLQEHNIDSSPC----SEDSHLGKMLGTSSPSIKSESDISSSNHHLVNG 677
            ||                   .:.|.||    |.:|....:...|  |::|.|..||:.::..:.
  Fly   289 PL-------------------TLPSVPCLLEASSESAFTCLPAAS--SVESTSSSSSARYYDDSN 332

  Fly   678 VRASDSLLTYSPD 690
            ...||..|....|
  Fly   333 NEPSDYSLKPKQD 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..530	CDD:290200	12/26 (46%)
		C2H2 Zn finger	519..541	CDD:275368	11/21 (52%)
		zf-H2C2_2	533..560	CDD:290200	17/26 (65%)
		C2H2 Zn finger	549..572	CDD:275368	13/22 (59%)
		C2H2 Zn finger	580..601	CDD:275368	17/20 (85%)
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	9/19 (47%)
		zf-H2C2_2	183..207	CDD:290200	12/25 (48%)
		COG5048	192..>271	CDD:227381	53/81 (65%)
		C2H2 Zn finger	198..218	CDD:275368	11/21 (52%)
		zf-H2C2_2	210..237	CDD:290200	17/26 (65%)
		C2H2 Zn finger	226..248	CDD:275368	13/22 (59%)
		C2H2 Zn finger	256..277	CDD:275368	17/20 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466592
Domainoid	1	1.000	48	1.000	Domainoid score	I8021
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D56141at7147
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.850