Protein Alignment ci and Glis2

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: XP_038941774.1
• Gene: Glis2 / 302946
• RGDID: 1309177
• Length: 522
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 148/538 - (27%)
• Similarity: 210/538 - (39%)
• Gaps: 159/538 - (29%)

  Fly   330 ITTSPTVTKDVSQVPAAAFSLKNLD--DAREKKGPFKDVVPEQPSSTSGGVAQVEADSASSQLSD 392
            :..|||.....|..|....:.|..:  |.|....|..|:....||.       :::.:.||.||.
  Rat    43 VDDSPTPGSPGSPPPGFLLNPKFPEKLDGRFSAAPLVDLSLSPPSG-------LDSPNGSSSLSP 100

  Fly   393 RCYNN-------------VVNNITGIPGDVKVNSRLDEYINCGSISIPSNEY------DCANADT 438
            ....|             .:..:.|:|...:....|.   :.|::.:|::.:      .|.:.:.
  Rat   101 ERQGNGDLPPLPTAVDFQPLRYLDGVPSSFQFFLPLG---SGGALHLPASSFLTPPKDKCLSPEL 162

  Fly   439 TDIKDEPGDFIETNCHWRSCRIEFITQDELVKHINNDHIQTNKKA-FVCRWEDCTRGEKPFKA-Q 501
            ...|       :..|.|..|...|....:||.|:|:.|::..:.| :.|.||.|.|..:.|.| :
  Rat   163 PLAK-------QLVCRWAKCNQLFELLQDLVDHVNDHHVKPEQDARYCCHWEGCARHGRGFNASR 220

  Fly   502 YMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAK 566
            |.:::|:|.||.||||:|  ..|.|::|||||||.|.|||||||||.|.|.||:|.:||:|||.|
  Rat   221 YKMLIHIRTHTNEKPHRC--PTCNKSFSRLENLKIHNRSHTGEKPYVCPYEGCNKRYSNSSDRFK 283

  Fly   567 HQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHG--------------------------- 604
            | .|||..:|||.||.|||.||||||||||||:| .||
  Rat   284 H-TRTHYVDKPYYCKMPGCHKRYTDPSSLRKHIK-AHGHFVSHEQQELLQLRPPPKPPLPTPDSG 346

  Fly   605 -------------AEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGT 656
                         |..:......||||..|...|            ::.:..|......|..:|.
  Rat   347 SYVSGAQIIIPNPAALFGGPSLPGLPLPLAPGPL------------DLSALACGNGGGGGGGMGP 399

  Fly   657 SSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENLNLDDGWNCDDDVDVADLPIVLRAMV 721
            ..|.                      |:|   |.:||:|..|...:....    ..||:|
  Rat   400 GLPG----------------------SVL---PLNLAKNPLLPSPFGAGG----LGLPVV----- 430

  Fly   722 NIGNGNASASTIGGSVLARQRFRGRLQTKGINSSTIMLCNIPESNRTFGISELN---QRITELKM 783
                     |.:|||  |..:..|.   ||..|       :|.  |..|:.:..   :|....:.
  Rat   431 ---------SLLGGS--AGSKAEGE---KGRGS-------VPA--RVLGLEDHKTSLERTERSRS 472

  Fly   784 EPGTDAEIKIPKLPNTTI 801
            .|..|.   :|.||.|.:
  Rat   473 RPSPDG---LPLLPGTVL 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	9/17 (53%)
		SFP1	<513..603	CDD:227516	60/89 (67%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	18/26 (69%)
		C2H2 Zn finger	549..572	CDD:275368	13/22 (59%)
		C2H2 Zn finger	580..601	CDD:275368	17/20 (85%)
Glis2	XP_038941774.1	C2H2 Zn finger	213..230	CDD:275368	5/16 (31%)
		COG5048	234..>328	CDD:227381	61/97 (63%)
		C2H2 Zn finger	238..258	CDD:275368	12/21 (57%)
		C2H2 Zn finger	266..288	CDD:275368	13/22 (59%)
		C2H2 Zn finger	296..318	CDD:275368	18/22 (82%)