Protein Alignment ci and zic1

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_571008.1
• Gene: zic1 / 30096
• ZFINID: ZDB-GENE-000208-4
• Length: 442
• Species: Danio rerio
• Alignment Length: 505
• Identity: 157/505 - (31%)
• Similarity: 213/505 - (42%)
• Gaps: 130/505 - (25%)

  Fly   252 ASGSYGHISATALNPMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVA------ASG---FSIGH 307
            |...|..|..|......| |||                 ..:|.::||      |.|   |.|.|
Zfish     5 AGPQYPTIGVTTFGSTRH-HST-----------------GEVTDREVALGINPFADGMGAFKINH 51

  Fly   308 MP---TSASLRVNDVHPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPFKDVVPE 369
            ..   .|.....:...|..:.:.:.....||   .||....|||: ...|.....:| |.|....
Zfish    52 SSHDLGSGQTAFSSQAPGYAAAALGHHHHPT---HVSSYSTAAFN-STRDFLFRNRG-FGDATSA 111

  Fly   370 QPS---STSGGVA--QVEADSAS--------SQLSDRCYNNVVNN--ITGIPGDVKVNSRLDEYI 419
            |.|   |.:|..|  ...:|:|.        .|.:....:||||:  ..|..||  :..|.::|
Zfish   112 QHSLFASAAGSFAGPHGHSDAAGHLLFPGLHEQAATHASSNVVNSQMRLGFSGD--MYGRAEQY- 173

  Fly   420 NCGSISIPSNE---------YDCANADTTDIKDEPGDFI---------ETNCHW----------R 456
              |.::.|.:|         |...|.:.. .....|.|.         |..|.|          :
Zfish   174 --GHVASPRSEHYASTQLHGYGPMNMNMA-AHHGAGAFFRYMRQPIKQELICKWIEPEQLTNPKK 235

  Fly   457 SCRIEFITQDELVKHINNDHI----QTNKKAFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPH 517
            ||...|.|..|||.|:..:|:    |:|   .:|.||:|.|..|||||:|.||.|:|.||||||.
Zfish   236 SCNKTFSTMHELVTHLTVEHVGGPEQSN---HICFWEECGREGKPFKAKYKLVNHIRVHTGEKPF 297

  Fly   518 KCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKA 582
            .|.|.||.|.::|.||||.|.|:||||||:.||:.||.:.|:|:|||.||.: .|:::|||:||.
Zfish   298 PCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMH-VHTSDKPYLCKM 361

  Fly   583 PGCTKRYTDPSSLRKHVKTVHGAEFYANKKHKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSED 647
              |.|.||.|||||||:| ||      ....:|...:.|.|...::::...:      .||.:|:
Zfish   362 --CDKSYTHPSSLRKHMK-VH------ESSSQGSQPSPAASSGYESSTPPTI------VSPSTEN 411

  Fly   648 SHLGKMLGTSSPSIKSESDISSSNHHLVNGVRASDSLLTYSPDDLAENLN 697
            .        ||.||   |..||:.||            |.|...|:.|.|
Zfish   412 Q--------SSSSI---SPASSTVHH------------TSSHSTLSSNFN 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	11/17 (65%)
		SFP1	<513..603	CDD:227516	51/89 (57%)
		C2H2 Zn finger	519..541	CDD:275368	12/21 (57%)
		zf-H2C2_2	533..560	CDD:463886	16/26 (62%)
		C2H2 Zn finger	549..572	CDD:275368	11/22 (50%)
		C2H2 Zn finger	580..601	CDD:275368	13/20 (65%)
zic1	NP_571008.1	zf_ZIC	214..259	CDD:436441	12/44 (27%)
		C2H2 Zn finger	269..291	CDD:275368	13/21 (62%)
		SFP1	<293..377	CDD:227516	50/86 (58%)
		C2H2 Zn finger	299..321	CDD:275368	12/21 (57%)
		C2H2 Zn finger	329..351	CDD:275368	11/22 (50%)
		C2H2 Zn finger	359..379	CDD:275368	14/22 (64%)