Protein Alignment ci and tra-1

DIOPT Version :10

• Sequence 1: NP_524617.3
• Gene: ci / 43767
• FlyBaseID: FBgn0004859
• Length: 1397
• Species: Drosophila melanogaster
• Sequence 2: NP_001022880.2
• Gene: tra-1 / 176548
• WormBaseID: WBGene00006604
• Length: 1110
• Species: Caenorhabditis elegans
• Alignment Length: 1212
• Identity: 295/1212 - (24%)
• Similarity: 434/1212 - (35%)
• Gaps: 356/1212 - (29%)

  Fly   299 AASGFSIGHMPTSASLRVNDVHPNLSDSHIQITTSPTVTKDVSQVPAAAFSLKNLDDAREKKGPF 363
            |.|.|....:|.|        |..||:   .:..||.....|:|...|:........|   .|..
 Worm    69 ATSNFIQSSVPPS--------HQTLSN---PLQLSPPAEASVAQQSGASQVFPTFQAA---LGAS 119

  Fly   364 KDVVPEQPSSTSGGVAQVEADSASSQLSDRCYNNVVNNITGIPGDVKVNSRLDEYIN-------C 421
            .|.: .||::||...:. .|.::|.....:..|....|.:.:...|..|.||.  ||       .
 Worm   120 SDEL-LQPNATSSSTSS-SASTSSIVPVVKFTNQTAPNGSTVATSVGQNVRLT--INGKRVGRPP 180

  Fly   422 GSISIPSNEYDCANADTT-DIKDEPGDFIETNCHWRSCRIEFITQDELVKHINNDHIQTNKK--- 482
            |:...|.|  :.||:..: :..|..||. :..|.|:||...|.|...||.|:...|:|:.::
 Worm   181 GTFKRPQN--NAANSSNSGNDSDMMGDH-DLTCRWKSCNSSFQTLKALVDHVQESHVQSTEQEHH 242

  Fly   483 AFVCRWEDCTRGEKPFKAQYMLVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPY 547
            |:.|.||.|.|.| .|||.|||:||:||||||||:||.:.||.|.||||||||||.|:|||||||
 Worm   243 AWRCEWEGCDRNE-TFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRTHTGEKPY 306

  Fly   548 TCEYPGCSKAFSNASDRAKHQNRTHSNEKPYICKAPGCTKRYTDPSSLRKHVKTVHGAEFYANKK 612
            .||:..|.|||||||||||||||||||.|||.|:.|.|||.||||||||||:|.|||.:.| .|.
 Worm   307 KCEFADCEKAFSNASDRAKHQNRTHSNLKPYSCQIPQCTKSYTDPSSLRKHIKAVHGDDEY-EKA 370

  Fly   613 HKGLPLNDANSRLQQNNSRHNLQEHNIDSSPCSEDSHLGKMLGTSSPSIKSESDISSSN------ 671
            .|..|.|.:|.|         ..:|.: :.|....||.......|..|:.:.|.:...|
 Worm   371 KKSRPANYSNRR---------RPDHRL-APPTGAMSHPYLATPNSGASVVAHSSVHQQNFINMAL 425

  Fly   672 ---HHLVNGVRASDSLLTYSPDDLAENLNLDDGWNCDDDVDVADLPIVLRAMVNIGNGNASASTI 733
               ||  |..||...:....              |....:|.|......:|.   .:..|.|..:
 Worm   426 AQHHH--NAQRAQQLMAATG--------------NVMPMMDPASAAAAAQAQ---AHHQAQAQML 471

  Fly   734 ------------GGSVLARQRFRGRLQTKGINSSTIMLCN---------------IPESNRTFGI 771
                        ...:.|:.:.:..:|...:..:.::|.|               :|.|.....:
 Worm   472 QTHMMQQAQIQAAAQMQAQVQHQAAMQAHAMQQAQMVLQNNLLGAQSLLSPFSPLLPPSRAPNVM 536

  Fly   772 SELNQRITELKMEPGTD---------AEIKIPKLPNTTIGG-------YTE--------DPLQNQ 812
            :.|....|...:.|..|         ..:..|..|...:..       :.|        :|||.|
 Worm   537 AMLQTPPTPTSVAPMFDIMTSRAPMAPVVSAPTAPAPLVPAPVPASPVFDELREQMREVEPLQQQ 601

  Fly   813 TSFRNTVSNKQG----------------TVSGSIQGQFRRDSQNSTASTYYGSMQSRRSSQSSQV 861
            ........:.|.                |.||::  ...|...|.... :.||..||.||.|.
 Worm   602 QQQEPMDQDLQDIRVDGDSDDEDEEEPRTPSGAL--LLPRGGNNGDGG-FGGSGSSRASSGSG-- 661

  Fly   862 SSIPTMRPNPSCNSTASFYDPISPGCSRRSSQMSNGANCNSFTSTSGLPVLNKESNKSLNACINK 926
                ||..:.:         |||...||.|.....|  ..||.....|.:.....|:.|.:
 Worm   662 ----TMELSAA---------PISQNGSRASGSGERG--MRSFLIADILQLAADFQNERLLS---- 707

  Fly   927 PNIGVQGVGIYNSSLPPPPSSHLIATNLKRLQRKDSEYHNFTSGRFSVPSYMHSLHIKNNK--PV 989
               .|..:.|:::                   |.....||           ::.::|:.:|  |:
 Worm   708 ---DVLDLAIFDT-------------------RDVRSLHN-----------IYQVYIRAHKAIPI 739

  Fly   990 GENEFDKAIASNARRQTDPVPNINLDPLTNISRFSTTPHSFDINVGKTNNIASSINKDNLRKDLF 1054
            .....|       ..:|..:.|:..||..|.:....:|...|.:......||.
 Worm   740 TRRPLD-------WNETHQLHNLYHDPRFNRAEHQDSPAIRDRDTRFWRTIAE------------ 785

  Fly  1055 TVSIKADMAMTSDQHPNERINLDEVEELILPDEML----------QYL-NLVKDDTNHLEKEHQA 1108
                    |.|..|...|.:.||:.:|... |||:          |:: ....||.:..|.|...
 Worm   786 --------ANTMRQRQIEPVPLDDDDEGYF-DEMVHRVQNGRLNEQFMEGFESDDDDGFEDEDDV 841

  Fly  1109 VPVGSNVSETIASNHYREQSNIYYTNKQILTPPSNVDIQPNTTKFTVQDKFAMTAVGGSFSQREL 1173
            ..:|..|        ||.:..:    ::.....:|:|||...|        |...|||...:.:
 Worm   842 PGLGIAV--------YRGRRRV----RREALKQANLDIQEAET--------AGRNVGGFGDEED- 885

  Fly  1174 STLAVPNEHGHAKCESF--HH--------------------------QSQKYMNTDIGSKQQSAL 1210
                 .|..||.:..||  |:                          :::|.:.||...|:..|:
 Worm   886 -----RNNRGHDQDRSFLDHYYPPMVVVVETESPQIVRDQEMMRQFEEAKKNVETDEIKKRAEAM 945

  Fly  1211 -----PSAHQRQT---EKSNYNQI--IDSSMTSLPELNVDSIYPR-------------------N 1246
                 .|.|..:|   :::.:::.  :..|:.....::||....|                   :
 Worm   946 QFGTSSSHHHTKTLLIQRALFDKTSSVRRSLLQFITISVDQEELRQSCHATSAPQGAHVVHNVVD 1010

  Fly  1247 ETENIFKVHGDHDNEIQCGIISQSQMSPSTNLNNDGQFSTVNMQPITTSKLFPPEPQKIVCDTQA 1311
            |.::|.:...|.:|.|   ::|....:||......|..                        |.|
 Worm  1011 EFDSIMRAQEDSNNRI---LLSLDIPAPSAVTGVSGSI------------------------THA 1048

  Fly  1312 SNTSVMHLDTYQRTLEYVQSCQNWMETNNTSTNQIQSLPGMP 1353
            .| |.:.|...|.|    .|..:|...:    :.|.:||..|
 Worm  1049 DN-SALQLQQEQPT----SSFSSWFPED----DPIYALPPPP 1081

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ci	NP_524617.3	zf-H2C2_2	503..>521	CDD:463886	14/17 (82%)
		SFP1	<513..603	CDD:227516	68/89 (76%)
		C2H2 Zn finger	519..541	CDD:275368	15/21 (71%)
		zf-H2C2_2	533..560	CDD:463886	19/26 (73%)
		C2H2 Zn finger	549..572	CDD:275368	18/22 (82%)
		C2H2 Zn finger	580..601	CDD:275368	15/20 (75%)
tra-1	NP_001022880.2	COG5048	<177..358	CDD:227381	104/184 (57%)
		C2H2 Zn finger	246..270	CDD:275368	15/24 (63%)
		SFP1	<272..362	CDD:227516	68/89 (76%)
		C2H2 Zn finger	278..300	CDD:275368	15/21 (71%)
		zf-H2C2_2	292..319	CDD:463886	19/26 (73%)
		C2H2 Zn finger	308..331	CDD:275368	18/22 (82%)
		C2H2 Zn finger	339..362	CDD:275368	16/22 (73%)