DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ci and klu-1

DIOPT Version :9

Sequence 1:NP_524617.3 Gene:ci / 43767 FlyBaseID:FBgn0004859 Length:1397 Species:Drosophila melanogaster
Sequence 2:NP_493611.2 Gene:klu-1 / 173366 WormBaseID:WBGene00013970 Length:543 Species:Caenorhabditis elegans


Alignment Length:417 Identity:108/417 - (25%)
Similarity:160/417 - (38%) Gaps:84/417 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   204 GGSIRASISRKRALSSSPYSD---SFDINSMIRFSPNSLATIMNGSRGSSAASGSYGHISATALN 265
            |.|.|:|.|...: |...|.|   .||.......||....|..:|: ..|.::.|..|.|..|.:
 Worm    98 GSSARSSFSSTTS-SFLTYRDRSVDFDEAGKELISPFDCDTNCSGT-PYSLSTNSGNHFSFEARS 160

  Fly   266 PMSHVHSTRLQQIQAHLLRASAGLLNPMTPQQVAASGFSIGHMPTSASLRVNDVHPNLSDSHIQI 330
            ..|..|||      ||.             .|:.|:|.:. .:....|...:|:.|...|....:
 Worm   161 VSSLGHST------AHF-------------NQLLAAGAAY-ELSRERSRSESDMQPTQEDDVRHL 205

  Fly   331 TTSPTVTKDVSQVPAAAF--SLKNLDDAREKKGPFKDVVPE----QPSSTSGGVAQVEADSASSQ 389
            .||.......::.|...|  .:|............::.|.:    :||  ||...:.:.::.:|.
 Worm   206 NTSTISVPIYAKKPLHKFGGEIKRSSSTPPPTSDEREQVEQRLLLRPS--SGMEIKKDLETTNSF 268

  Fly   390 LSD-------RCYNNVVNNITGIPGDVKVNSRLDEYINCGSISIPS--NEYDCANADTTDI-KDE 444
            :|.       ...|..:.|:        :.:|..|  :|.:||.|.  ..:..:..|.|.. :|:
 Worm   269 VSSWAREQIFAMQNATMYNL--------LTARSAE--DCSTISTPGPLKVFPRSKDDMTFAPRDD 323

  Fly   445 PGDFIETNCHWRSCRIEFITQDELVKHINNDHIQTNKKAFVCRWED------CTRGEKPFKAQYM 503
            .....:.......|...|...|.|.|||.:.|.|.:     |..:|      |....|.|....|
 Worm   324 SSRAKQMQYPCTLCGQAFAVHDRLAKHIASRHRQRS-----CTLDDASKVHKCNMCSKSFSRSDM 383

  Fly   504 LVVHMRRHTGEKPHKCTFEGCFKAYSRLENLKTHLRSHTGEKPYTCEYPGCSKAFSNASDRAKHQ 568
            |..|||.|||.||:.|  ..|.:.:||.::|.||||:|||||||.|  |.|:.:.|.....::|.
 Worm   384 LTRHMRLHTGAKPYSC--PTCNQVFSRSDHLSTHLRTHTGEKPYAC--PMCNYSASRRDMISRHM 444

  Fly   569 NRTHSNEKPYICKAPGCTKRYTDPSSL 595
             ||||               .||.||:
 Worm   445 -RTHS---------------LTDDSSI 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ciNP_524617.3 zf-H2C2_2 503..530 CDD:290200 12/26 (46%)
C2H2 Zn finger 519..541 CDD:275368 9/21 (43%)
zf-H2C2_2 533..560 CDD:290200 15/26 (58%)
C2H2 Zn finger 549..572 CDD:275368 6/22 (27%)
C2H2 Zn finger 580..601 CDD:275368 4/16 (25%)
klu-1NP_493611.2 C2H2 Zn finger 334..354 CDD:275368 7/19 (37%)
zf-C2H2 369..391 CDD:278523 8/21 (38%)
C2H2 Zn finger 371..391 CDD:275368 8/19 (42%)
zf-H2C2_2 383..408 CDD:290200 12/26 (46%)
COG5048 395..>448 CDD:227381 25/57 (44%)
C2H2 Zn finger 399..419 CDD:275368 9/21 (43%)
zf-H2C2_2 411..436 CDD:290200 15/26 (58%)
C2H2 Zn finger 427..447 CDD:275368 6/22 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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