DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PlexB and LOC108179158

DIOPT Version :9

Sequence 1:	NP_001245400.1	Gene:	PlexB / 43766	FlyBaseID:	FBgn0025740	Length:	2051	Species:	Drosophila melanogaster
Sequence 2:	XP_017210788.1	Gene:	LOC108179158 / 108179158	-ID:	-	Length:	321	Species:	Danio rerio

Alignment Length:	383	Identity:	72/383 - (18%)
Similarity:	126/383 - (32%)	Gaps:	155/383 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 FAGATNKILKLNEN----LRVLAEAVTGPLHDSPQCHAGGCPEDIETSLVNNFNKI-LVVSYAHD 159
            |.....|:..|.||    :|          ||..:       |..:..:.|:.:.: ::|.:..:
Zfish    30 FVVGNGKLFVLTENRLYQMR----------HDLSE-------EKKKNDINNSTHPVNILVPFDDN 77

  Fly   160 GILIACGSIRQGACEIYSLPRFPATPQFFAVPLAANDENASTY----AFVGPARYAWKEEDILYV 220
            |.||.||:...|.||:                |..||...|.|    .|:||..   .|:.:.::
Zfish    78 GTLITCGTYEDGYCEV----------------LDINDIKNSIYYESNLFIGPKE---TEKSVAFI 123

  Fly   221 GTTFTNVGDYRHDVPAISSRRLDD---------------------LNYAEFSIQ---QSIINIDV 261
            ..|.::    |:   .:..::||.                     |:|||...:   ||..| ||
Zfish   124 AGTSSS----RY---LLIGKKLDQSTSQSPVVRLWNTLQTQFGGILSYAEQGSEPAIQSTAN-DV 180

  Fly   262 KYRDHFLVDYIYGF---NSSEYAYFIIVQKKSHLADEAGYVTRLARICITDPNYDSYTEITVQCT 323
            |:.|        ||   :||:...|:..:..|.         |...:...:.:..:.:||
Zfish   181 KFVD--------GFQRASSSDLYLFLNTKTDSE---------RKVHVLWMNSSKSTKSEI----- 223

  Fly   324 ATENNVDYNIVRDAKVTPASHK----LAQKMGIKKDDHVL-VTVFSPSREISNQPESKSAMCIYS 383
                   :..::.|.:...|.|    |.....|..:..|: ..|||...:  ..||: :|:.:|:
Zfish   224 -------FKSLQSAVIKCCSDKARPVLVSSAVIPSEKAVIWAGVFSAQDQ--QDPEN-TALALYN 278

  Fly   384 IKDIEDMFIENIHLCFNGTTKDRNLGYISGTINDGRCPIVGSLGNIYNFCSVGLKISG 441
            |..|:                                      |.:..||:.|.::.|
Zfish   279 ISRIQ--------------------------------------GRVKEFCAAGERMCG 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PlexB	NP_001245400.1	Sema_plexin_like	86..534	CDD:200497	72/383 (19%)
		PSI	535..586	CDD:279745
		PSI	683..730	CDD:214655
		PSI	836..877	CDD:214655
		IPT_plexin_repeat1	888..976	CDD:238585
		IPT_plexin_repeat2	977..1095	CDD:238584
		IPT_plexin_repeat3	1097..1211	CDD:238586
		Plexin_cytopl	1452..2017	CDD:285529
LOC108179158	XP_017210788.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D90434at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010