DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod and Pabpc5

DIOPT Version :9

Sequence 1:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_444344.1	Gene:	Pabpc5 / 93728	MGIID:	2136401	Length:	381	Species:	Mus musculus

Alignment Length:	266	Identity:	56/266 - (21%)
Similarity:	113/266 - (42%)	Gaps:	46/266 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 VFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKS-VLIAFDTSTGAEAVLQAKPKALTLG 240
            :|:.||.....::.|..||:.||.:.:.:...:.||:|. ..:.||:...|...:. ....:.|.
Mouse   107 IFIKNLDKTIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIW-HMNGVRLN 170

  Fly   241 DNVLSV----------SQPRNKEENNERTVVVGLIGPNITKDDLKTFFEKVAPVEAVTI---SSN 292
            :..:.|          ::.|.:|......|.|...|.:|..:.|...|.:..|.|:|.:   ::.
Mouse   171 NRQVYVGRFKFPEERAAEVRTRERATFTNVFVKNFGDDIDDEKLNKLFSEYGPTESVKVIRDATG 235

  Fly   293 RLMPRAFVRLASVDDIPKA-LKLHSTELFSRFITVRRISQESISRTSEL---------------- 340
            :.....|||..:.:...|| |:||...:..:.:.|.| :|:.|.|.:||
Mouse   236 KSKGFGFVRYETHEAAQKAVLELHGKSIDGKVLCVGR-AQKKIERLAELRRRFERLKLKEKNRPS 299

  Fly   341 --TLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVCSK------AVLAFVTFKQSDAATKALAQ 397
              .:.::|:  .|:.:.:.|::.|..||.:....|:...      .|:.|.:|::   |.||:.:
Mouse   300 GVPIYIKNL--DETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEE---ACKAVDE 359

  Fly   398 LDGKTV 403
            ::|:.:
Mouse   360 MNGRII 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	15/67 (22%)
		RRM_SF	260..327	CDD:240668	17/70 (24%)
		RRM_SF	342..411	CDD:240668	14/68 (21%)
		RRM_SF	422..>465	CDD:302621
Pabpc5	NP_444344.1	RRM1_I_PABPs	21..97	CDD:240824
		ELAV_HUD_SF	28..270	CDD:273741	35/163 (21%)
		RRM2_I_PABPs	103..178	CDD:240825	16/71 (23%)
		RRM3_I_PABPs	197..276	CDD:240826	20/79 (25%)
		RRM_SF	300..376	CDD:302621	14/71 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910