DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod and Pabpc6

DIOPT Version :9

Sequence 1:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001099678.1	Gene:	Pabpc6 / 292295	RGDID:	1311201	Length:	643	Species:	Rattus norvegicus

Alignment Length:	425	Identity:	92/425 - (21%)
Similarity:	147/425 - (34%)	Gaps:	137/425 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 SEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKSV- 216
            |:.:..:.|..||.|          ||.||......|.|...|:.||.:.:.:...:.||:|..
  Rat    87 SQRDPSLRKSGVGNI----------FVKNLDRSIDSKTLYDTFSAFGNILSCKVVCDENGSKGYG 141

  Fly   217 LIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNERTVVVGLIGPNITKDDLKTFFEKV 281
            .:.|:|...||..:: |...:.|                |:|.|.||
  Rat   142 FVHFETQEEAERAIE-KMNGMFL----------------NDRKVFVG------------------ 171

  Fly   282 APVEAVTISSNRLMPRAFVRLASVDDIPKALKLHSTELFSRFITVRRISQESISRTSELTLV-VE 345
                                                    ||.:.|....|..:|..|.|.| ::
  Rat   172 ----------------------------------------RFKSRRDRQAELGARAKEFTNVYIK 196

  Fly   346 NVGKHESYSSDALEKIFKKFGDVEEIDVVCSKA----VLAFVTFKQSDAATKALAQLDGKTVN-- 404
            |:|  |....:.|:.:|.:||....:.|:..::    ...||:|::.:.|.||:.:::||.:|
  Rat   197 NLG--EDMDDERLQDLFSRFGPALSVKVMTDESGKSKGFGFVSFERHEDARKAVDEMNGKDLNGK 259

  Fly   405 ---------KFEWKL---HRF---------------ERST--SGRAILVTNLTSDATEADLRKVF 440
                     |.|.:.   |:|               :||.  .|..:.|.||.....:..|||.|
  Rat   260 QIYVGRAQKKVERQTELKHKFGQMKQDKPKIEQVPQDRSVRCQGVNLYVKNLDDGIDDERLRKEF 324

  Fly   441 NDSGEIES--IIMLGQKA----VVKFKDDEGFCKSFL-ANESIVNNAPIFIEPNSLLKHRLLKKR 498
            :..|.|.|  :.|.|.::    .|.|...|...|:.. .|..||...|:::    .|..|..:::
  Rat   325 SPFGTITSAKVTMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV----ALAQRKEERQ 385

  Fly   499 LAIGQTRAPRKFQKDTKPNFGKKPFNKRPAQENGG 533
            ..:......|.......||.|..||  :|||...|
  Rat   386 AHLSNQYMQRMASTSAVPNPGINPF--QPAQGLSG 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	18/67 (27%)
		RRM_SF	260..327	CDD:240668	5/66 (8%)
		RRM_SF	342..411	CDD:240668	20/87 (23%)
		RRM_SF	422..>465	CDD:302621	14/48 (29%)
Pabpc6	NP_001099678.1	PABP-1234	11..622	CDD:130689	92/425 (22%)
		RRM1_I_PABPs	12..91	CDD:240824	1/3 (33%)
		RRM2_I_PABPs	97..172	CDD:240825	26/159 (16%)
		RRM3_I_PABPs	190..269	CDD:240826	19/80 (24%)
		RRM4_I_PABPs	303..380	CDD:240827	22/80 (28%)
		PABP	555..621	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910