DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod and Pabpc2

DIOPT Version :9

Sequence 1:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001099621.1	Gene:	Pabpc2 / 291615	RGDID:	1310759	Length:	630	Species:	Rattus norvegicus

Alignment Length:	265	Identity:	62/265 - (23%)
Similarity:	111/265 - (41%)	Gaps:	45/265 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 VFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKS-VLIAFDTSTGAEAVLQAKPKALTLG 240
            ||:.||.....:|.|...|:.||.:.:.:...:.||:|. ..:.|:|...||..:: |...:.|.
  Rat   101 VFIKNLNKTIDNKALYDTFSAFGNILSCKVVCDENGSKGHGFVHFETEEAAERAIE-KMNGMLLN 164

  Fly   241 DNVLSVSQPRNKEENNERTVVVGLIGPNITKDDLKTF---------------FEKVAPVEAVTIS 290
            |..:.|.|.::::   ||...:|......|...:|.|               |.:|..|:.:|..
  Rat   165 DRKVFVGQFKSRK---EREAELGTRTKEFTNVYIKNFGDRMDDKTLNGLFGRFGQVLSVKVMTDE 226

  Fly   291 SNRLMPRAFVRLASVDDIPKAL-KLHSTELFSRFITV-----------------RRISQESISRT 337
            ..:.....||.....:|..||: :::..||..:.|.|                 .:::|:...|.
  Rat   227 GGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKHIYVGPAQKKVDRHIELKRKFEQVTQDRGIRY 291

  Fly   338 SELTLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVC----SKAVLAFVTFKQSDAATKALAQL 398
            ..:.|.|:|:  .:....:.|:|.|..||.:....|:.    ||. ..||.|...:.||||::::
  Rat   292 QGINLYVKNL--DDGIDDERLQKEFSPFGTITSTKVMTEGGRSKG-FGFVCFSSPEEATKAVSEM 353

  Fly   399 DGKTV 403
            :|:.|
  Rat   354 NGRIV 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	19/67 (28%)
		RRM_SF	260..327	CDD:240668	17/99 (17%)
		RRM_SF	342..411	CDD:240668	20/66 (30%)
		RRM_SF	422..>465	CDD:302621
Pabpc2	NP_001099621.1	PABP-1234	11..609	CDD:130689	62/265 (23%)
		RRM1_I_PABPs	12..91	CDD:240824
		RRM2_I_PABPs	97..171	CDD:240825	19/70 (27%)
		RRM3_I_PABPs	190..269	CDD:240826	16/78 (21%)
		RRM4_I_PABPs	293..370	CDD:240827	20/69 (29%)
		PABP	542..608	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910