DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod and Pabpc4

DIOPT Version :9

Sequence 1:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_570951.2	Gene:	Pabpc4 / 230721	MGIID:	2385206	Length:	660	Species:	Mus musculus

Alignment Length:	305	Identity:	69/305 - (22%)
Similarity:	122/305 - (40%)	Gaps:	60/305 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 SEENRGIPKVKVGKIPLGTPKNQIVFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKS-V 216
            |:.:..:.|..||.          ||:.||.....:|.|...|:.||.:.:.:...:.||:|. .
Mouse    87 SQRDPSLRKSGVGN----------VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYA 141

  Fly   217 LIAFDTSTGAEAVLQAKPKALTLGDNVLSVSQPRNKEENNER---------TVVVGLIGPNITKD 272
            .:.|:|...|:..:: |...:.|.|..:.|.:.::::|....         .|.:...|..:...
Mouse   142 FVHFETQEAADKAIE-KMNGMLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDG 205

  Fly   273 DLKTFFE---KVAPVEAVTISSNRLMPRAFVRLASVDDIPKAL-KLHSTELFSRFITVRR----- 328
            :||..|.   |...|:.:..||.:.....||.....:|..||: :::..|:..:.|.|.|
Mouse   206 NLKELFSQFGKTLSVKVMRDSSGKSKGFGFVSYEKHEDANKAVEEMNGKEMSGKAIFVGRAQKKV 270

  Fly   329 ------------ISQESISRTSELTLVVENVGKHESYSSDALEKIFKKFGDVEEIDVVC----SK 377
                        :.||.|||...:.|.::|:  .::...:.|.:.|..||.:....|:.    ||
Mouse   271 ERQAELKRKFEQLKQERISRYQGVNLYIKNL--DDTIDDEKLRREFSPFGSITSAKVMLEDGRSK 333

  Fly   378 AVLAFVTFKQSDAATKALAQLDGKTV-----------NKFEWKLH 411
            . ..||.|...:.||||:.:::|:.|           .|.|.|.|
Mouse   334 G-FGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAH 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	18/67 (27%)
		RRM_SF	260..327	CDD:240668	16/70 (23%)
		RRM_SF	342..411	CDD:240668	21/83 (25%)
		RRM_SF	422..>465	CDD:302621
Pabpc4	NP_570951.2	PABP-1234	11..640	CDD:130689	69/305 (23%)
		RRM1_I_PABPs	12..91	CDD:240824	1/3 (33%)
		RRM2_I_PABPs	97..172	CDD:240825	21/85 (25%)
		RRM3_I_PABPs	190..269	CDD:240826	18/78 (23%)
		RRM4_I_PABPs	293..370	CDD:240827	18/79 (23%)
		PABP	572..639	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910