DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mod and PABPC4L

DIOPT Version :9

Sequence 1:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster
Sequence 2:	NP_001108206.3	Gene:	PABPC4L / 132430	HGNCID:	31955	Length:	370	Species:	Homo sapiens

Alignment Length:	258	Identity:	52/258 - (20%)
Similarity:	108/258 - (41%)	Gaps:	35/258 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 VFVTNLPNEYLHKDLVALFAKFGRLSALQRFTNLNGNKS-VLIAFDTSTGAEAVLQAKPKALTLG 240
            ||:.||.....:|.|...|:.||::.:.:..::..|:|. ..:.|...:.|:..::.....|..|
Human   100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKG 164

  Fly   241 DNVLSVSQPRNKEENNER---------TVVVGLIGPNITKDDLKTFFE---KVAPVEAVTISSNR 293
            ..|. |.:.:|:::....         .|.:...|.::..:.||..|.   |...|:.:|.||.:
Human   165 CKVF-VGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGK 228

  Fly   294 LMPRAFVRLASVDDIPKAL-KLHSTELFSRFITVRRISQESISRTSELTLVVENVGKH------- 350
            .....||...|.:...||: :::..::..:.|.|.| :|:.:.|.:||..:.|.:.:.
Human   229 SKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGR-AQKKVERQAELKQMFEQLKRERIRGCQG 292

  Fly   351 ---------ESYSSDALEKIFKKFGDVEEIDVVCSKAV---LAFVTFKQSDAATKALAQLDGK 401
                     ::...:.|...|..||.:..:.|:..:..   ...:.|...:.||||:.:::|:
Human   293 VKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621	15/67 (22%)
		RRM_SF	260..327	CDD:240668	16/70 (23%)
		RRM_SF	342..411	CDD:240668	12/79 (15%)
		RRM_SF	422..>465	CDD:302621
PABPC4L	NP_001108206.3	RRM	10..>369	CDD:330708	52/258 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910