Protein Alignment CG2003 and FEN2

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_009957.1
• Gene: FEN2 / 850394
• SGDID: S000000623
• Length: 512
• Species: Saccharomyces cerevisiae
• Alignment Length: 388
• Identity: 74/388 - (19%)
• Similarity: 118/388 - (30%)
• Gaps: 148/388 - (38%)

  Fly    99 WGTLGSSLLSALTTYGVY-AGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAY 161
            ||         |.|.|:| ...:|..||||..|.|.: .|:...|..|.:|....|.....|. :
Yeast   112 WG---------LLTLGMYKVTSFKHICAIRFFQALFESCTFSGTHFVLGSWYKEDELPIRSAI-F 166

  Fly   162 TGFDCGNVLAMYGAGMIAS---------SSLGW----------------------PGISYSAAGL 195
            ||  .|.|.:|:...|..|         ...||                      ||:....:.:
Yeast   167 TG--SGLVGSMFSGFMQTSIFTHLNGRNGLAGWRWLFIIDFCITLPIAIYGFIFFPGLPDQTSAV 229

  Fly   196 GLIWCGLWLLLGANKASDARFI-GEAEKAYIVGDIQRSERKGPKKME---IPWKGIFTSVPVYAL 256
                         :|.|..|:| .|.|..|       :.|:.|.:.|   :.|    :::|
Yeast   230 -------------SKFSMTRYIFNEQELHY-------ARRRLPARDESTRLDW----STIP---- 266

  Fly   257 LCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKKWMS 321
               |....|.......   .::.|...|...||:.|:      :|:....|.:
Yeast   267 ---RVLKRWHWWMFSL---VWVLGGENLGFASNSTFA------LWLQNQKYTL------------ 307

  Fly   322 LTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPN-HA 385
              ..|..|       |:.|                    .:||:.|.......::.|..:.: |.
Yeast   308 --AQRNNY-------PSGI--------------------FAVGIVSTLCSAVYMSKIPRARHWHV 343

  Fly   386 GILAGLMSSFTNLMALLTPLVVGVLV-TDPSQRSQWQIVFS--LAAGVLFTGNVIFLIWGTAV 445
            .:...|:.           ::|.||: .||...   ::|||  ...||.:.|..:|..|...:
Yeast   344 SVFISLVM-----------VIVAVLIRADPLNP---KVVFSAQYLGGVAYAGQAVFFSWANII 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	73/383 (19%)
FEN2	NP_009957.1	MFS_FEN2_like	32..450	CDD:340885	74/388 (19%)