Protein Alignment CG2003 and Slc17a6

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_445879.1
• Gene: Slc17a6 / 84487
• RGDID: 620531
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 497
• Identity: 144/497 - (28%)
• Similarity: 237/497 - (47%)
• Gaps: 45/497 - (9%)

  Fly    11 VPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNN-----SDPPHYNWSEEKKSYIL 70
            :||..:..:.:||   |...:..::.|:.||:|.|.|.:|.:.     .:...:||..|....|.
  Rat    67 LPRRYIIAIMSGL---GFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIH 128

  Fly    71 SSYYWGCALAQFPAGYLCKR------FGSKAVLFWGTLGSSLLSALTT-YGVYAGGWKAYCAI-- 126
            .|::||..:.|.|.||:..|      ||: |:|...||...:.||... ||         |.|
  Rat   129 GSFFWGYIITQIPGGYIASRLAANRVFGA-AILLTSTLNMLIPSAARVHYG---------CVIFV 183

  Fly   127 RLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISY 190
            |:||||.: ||:|..|...:.|.|..||:||...::.|...|.|:||..||::...: ||..:.|
  Rat   184 RILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFY 247

  Fly   191 SAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSER--KGPKKMEIPWKGIFTSVPV 253
            .....|::|...|||:.....:....|.:.|:.||...|..|..  ...:|.:.||:..|||:||
  Rat   248 VYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPV 312

  Fly   254 YALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKK 318
            ||::.|....||....:....|.|...|...::....:.||:|.|:|.::..:...|||.|..|:
  Rat   313 YAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQ 377

  Fly   319 WMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQ-KTLVLVLVTLSVGVSSAATIGSELNTIDLSP 382
            .:|.||:||..........|:::|   :||... :.:.:..:.|:||.|..|..|..:|.:|::|
  Rat   378 ILSTTTVRKIMNCGGFGMEATLLL---VVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAP 439

  Fly   383 NHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQ 447
            .:|.||.|:.:....|..::.|::||.:..:.| |.:||.||.:||.|.:.|.:.:.::.:...|
  Rat   440 RYASILMGISNGVGTLSGMVCPIIVGAMTKNKS-REEWQYVFLIAALVHYGGVIFYALFASGEKQ 503

  Fly   448 PWNESKESRR---------ELEPEEKPFHRAKLEIGTDNTDG 480
            ||.:.:|:..         ||:.|.....:..:..||..:.|
  Rat   504 PWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYG 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	132/438 (30%)
Slc17a6	NP_445879.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	132/441 (30%)