DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and SLC17A1

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_016866688.1	Gene:	SLC17A1 / 6568	HGNCID:	10929	Length:	517	Species:	Homo sapiens

Alignment Length:	469	Identity:	129/469 - (27%)
Similarity:	211/469 - (44%)	Gaps:	30/469 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PKTVPRLGLRHLQAGLLFYGLAANTVLQLN---VSVAVVAMTNET-------TS-----NNSDPP 57
            ||.||  |....:.||.|.....|.::...   :::.:|.|.|.|       ||     :|...|
Human    59 PKKVP--GFCSFRYGLSFLVHCCNVIITAQRACLNLTMVVMVNSTDPHGLPNTSTKKLLDNIKNP 121

  Fly    58 HYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAG-GWK 121
            .||||.:.:..||||..:|..:.|.|.||....:.:|.::.:....||:||.|.......| .|.
Human   122 MYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSVLSLLIPPAAGIGVAWV 186

  Fly   122 AYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGW 185
            ..|  |.:||..| :......:....|.|..||.||.:.:.:||..|..:.:...|:|. .||||
Human   187 VVC--RAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLLVTGVIC-ESLGW 248

  Fly   186 PGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKMEIPWKGIFTS 250
            |.:.|.....|...|.||.:|..:...|...|..:||.||...:  .::....:..:|.|.|..|
Human   249 PMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSL--VQQVSSSRQSLPIKAILKS 311

  Fly   251 VPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLL 315
            :||:|:........|....|....|.:::.:|.:::|.|...|:||:|..|:...:...::|..|
Human   312 LPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPYLFAWICGNLAGQLSDFFL 376

  Fly   316 RKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGSELNTIDL 380
            .:..:|:..:||.:|:.....||...:.|..:.....::|:.|: |:....|....|..:|.:|:
Human   377 TRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSSTFYSIVIFLI-LAGATGSFCLGGVFINGLDI 440

  Fly   381 SPNHAGILAGLMSSFTNLM-ALLTPLVVG-VLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGT 443
            :|.:.|.:.. .|:.|.:: .|:...:.| :|..||  .|.|...|.|.|.:..||.:.:||..|
Human   441 APRYFGFIKA-CSTLTGMIGGLIASTLTGLILKQDP--ESAWFKTFILMAAINVTGLIFYLIVAT 502

  Fly   444 AVTQPWNESKESRR 457
            |..|.|.:.|:..|
Human   503 AEIQDWAKEKQHTR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	122/451 (27%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	105/386 (27%)
SLC17A1	XP_016866688.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148646
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750