Protein Alignment CG2003 and SLC17A6

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 145/497 - (29%)
• Similarity: 237/497 - (47%)
• Gaps: 45/497 - (9%)

  Fly    11 VPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNN-----SDPPHYNWSEEKKSYIL 70
            :||..:..:.:||   |...:..::.|:.||:|.|.|.:|.:.     .:...:||..|....|.
Human    67 LPRRYIIAIMSGL---GFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIH 128

  Fly    71 SSYYWGCALAQFPAGYLCKR------FGSKAVLFWGTLGSSLLSALTT-YGVYAGGWKAYCAI-- 126
            .|::||..:.|.|.||:..|      ||: |:|...||...:.||... ||         |.|
Human   129 GSFFWGYIITQIPGGYIASRLAANRVFGA-AILLTSTLNMLIPSAARVHYG---------CVIFV 183

  Fly   127 RLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISY 190
            |:||||.: ||:|..|...:.|.|..||:||...::.|...|.|:||..||::...: ||..:.|
Human   184 RILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFY 247

  Fly   191 SAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSER--KGPKKMEIPWKGIFTSVPV 253
            .....|::|...|||:.....:....|.:.|:.||...|..|..  ...:|.:.||:..|||:||
Human   248 VYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPV 312

  Fly   254 YALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKK 318
            ||::.|....||....:....|.|...|...::....:.||:|.|:|.::..:...|||.|..|:
Human   313 YAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQ 377

  Fly   319 WMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQ-KTLVLVLVTLSVGVSSAATIGSELNTIDLSP 382
            .:|.||:||..........|:::|   :||... :.:.:..:.|:||.|..|..|..:|.:|::|
Human   378 ILSTTTVRKIMNCGGFGMEATLLL---VVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAP 439

  Fly   383 NHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQ 447
            .:|.||.|:.:....|..::.|::||.:..:.| |.:||.||.:||.|.:.|.:.:.|:.:...|
Human   440 RYASILMGISNGVGTLSGMVCPIIVGAMTKNKS-REEWQYVFLIAALVHYGGVIFYAIFASGEKQ 503

  Fly   448 PWNESKESRR---------ELEPEEKPFHRAKLEIGTDNTDG 480
            ||.:.:|:..         ||:.|.....:..:..||..:.|
Human   504 PWADPEETSEEKCGFIHEDELDEETGDITQNYINYGTTKSYG 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	133/438 (30%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	133/441 (30%)