Protein Alignment CG2003 and slc17a8

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001076304.1
• Gene: slc17a8 / 563467
• ZFINID: ZDB-GENE-060503-416
• Length: 590
• Species: Danio rerio
• Alignment Length: 519
• Identity: 155/519 - (29%)
• Similarity: 239/519 - (46%)
• Gaps: 54/519 - (10%)

  Fly     8 PKTVPRL------GL--RHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETT--SNNS---DPPHY 59
            ||..|.|      ||  |::.|.|...|...:..::.|:.||:|.|.|..|  .|.:   .|..:
Zfish    58 PKRSPPLLDCGCFGLPKRYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVMQPAQF 122

  Fly    60 NWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLL------SALTTYGVYAG 118
            ||..|....|..|::||..:.|.|.|::..:..:..|.......:|:|      :|...||
Zfish   123 NWDPETVGLIHGSFFWGYIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYG---- 183

  Fly   119 GWKAYCA--IRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIAS 180
                 |.  :|:||||.: ||:|..|...:.|.|..||:||...::.|...|.|:||..||::.
Zfish   184 -----CVMFVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILV- 242

  Fly   181 SSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSER--KGPKKMEIP 243
            ..:|||.:.|.....|:||...|:||..|..:....|.|.|:.||...|.....  ...:|.:.|
Zfish   243 QYVGWPSVFYIYGVFGIIWYIFWILLAYNSPAVHPTISEEERNYIETSIGEGANLMSSTEKFKTP 307

  Fly   244 WKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYL 308
            |:..|||:||||::.|....||....:....|.|...|....:....:.||:|.::|.::..:..
Zfish   308 WREFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGG 372

  Fly   309 IIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVG-EGQKTLVLVLVTLSVGVSSAATIG 372
            .:||.|..:|.:|.||:||..........|:::|   :|| ...:.:.:..:.|:||.|..|..|
Zfish   373 QLADFLRSRKILSTTTVRKIMNCGGFGMEATLLL---VVGFSHTRAVAISFLILAVGFSGFAISG 434

  Fly   373 SELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVI 437
            ..:|.:|::|.:|.||.|:.:....|..::.||:||.| |....|.:||.||.:|:.|.:||.:.
Zfish   435 FNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAL-TKHKTRLEWQHVFVIASMVHYTGVIF 498

  Fly   438 FLIWGTAVTQPW----NESKE-----SRRELEPEEKPFH------RAKLEIGTDNTDGNVVGLK 486
            :.|:.:...|.|    |.|.|     ...||..|.:|..      |.|....|||:.|...|.|
Zfish   499 YAIFASGEKQDWADPENTSDEKCGIIGEDELADETEPSSDSGLATRQKTYGTTDNSSGRKQGWK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	131/437 (30%)
slc17a8	NP_001076304.1	MFS_SLC17A6_7_8_VGluT	79..503	CDD:340940	131/437 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..590		12/37 (32%)