Protein Alignment CG2003 and SLC37A1

DIOPT Version :9

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_011527916.1
• Gene: SLC37A1 / 54020
• HGNCID: 11024
• Length: 577
• Species: Homo sapiens
• Alignment Length: 527
• Identity: 116/527 - (22%)
• Similarity: 188/527 - (35%)
• Gaps: 148/527 - (28%)

  Fly     7 IPKTVPRLGLRHLQAGLLF---YGLAANTVLQLN-VSV--------------AVVAMTNETTSNN 53
            :|.|.|...| ||....:|   :.|.|:..|... :|:              |.|..:::...:.
Human    39 LPHTSPCASL-HLYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSG 102

  Fly    54 SDPPHY--------NWSE-EKKSY--ILSS--YYWGCALA--QFPAGYLCKRFGSKAVLFWGTLG 103
            |..||.        .|:. :|.:|  :|.:  |.:.||.|  .:.:|.:.:|...:..|.:|.|.
Human   103 SAAPHQLPDNETDCGWAPFDKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLA 167

  Fly   104 SSLLSAL----TTYGVYAGGWKAYCAIRLLQGLCQVT-WPCIHQHLANWCPTAERTRLGAFAYTG 163
            |...:||    ..|.:::.|:  |...:::.||.|.| ||.:...|.||.....|..:.....:.
Human   168 SGAFTALFGLGYFYNIHSFGF--YVVTQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNSH 230

  Fly   164 FDCGNVLAMYGAGMIASSSLGW----PGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAY 224
            ...||:|....||...|:..|.    ||...:|.|   |.|.|:|:...|....:..:....|.|
Human   231 TSVGNILGSLIAGYWVSTCWGLSFVVPGAIVAAMG---IVCFLFLIEHPNDVRCSSTLVTHSKGY 292

  Fly   225 IVG--------DIQRSERKGPKKME--------------------IPWKG-------IFT---SV 251
            ..|        .|.:||:..|...|                    :|..|       .||   .:
Human   293 ENGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKI 357

  Fly   252 P---------VYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPF--------LL 299
            |         ::|.|.:.....|        ||.|::.|..||.|.....|.| |        :|
Human   358 PGVIEFSLCLLFAKLVSYTFLFW--------LPLYITNVDHLDAKKAGELSTL-FDVGGIFGGIL 413

  Fly   300 MWVM----------CYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTL 354
            ..|:          |.:.|::|...|        .:..|.:.:.|.|..:::|....:..|..||
Human   414 AGVISDRLEKRASTCGLMLLLAAPTL--------YIFSTVSKMGLEATIAMLLLSGALVSGPYTL 470

  Fly   355 VLVLVTLSVGVSSAATIGSELNTIDLSPN-HA-GILAGLMSSFTNLMALLTPLVVGVLVTDPSQR 417
            :...|:..:|...:           |..| || ..:..::....::.|.|.||:.|:|     ..
Human   471 ITTAVSADLGTHKS-----------LKGNAHALSTVTAIIDGTGSVGAALGPLLAGLL-----SP 519

  Fly   418 SQWQIVF 424
            |.|..||
Human   520 SGWSNVF 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	110/511 (22%)
		MFS	58..441	CDD:119392	101/458 (22%)
SLC37A1	XP_011527916.1	UhpC	51..543	CDD:225180	110/514 (21%)
		MFS	129..489	CDD:119392	84/392 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148670
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840