DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and CG15096

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_611376.1	Gene:	CG15096 / 37170	FlyBaseID:	FBgn0034394	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	460	Identity:	176/460 - (38%)
Similarity:	270/460 - (58%)	Gaps:	7/460 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPHYNWSEEKKSYILSSYYWGCA 78
            ||:||.|..|||:.|......::|:|||||||| :..|.|.|.|.|||||:.||.:|||::||..
  Fly    33 LGVRHFQVLLLFFALTVAYGCRVNLSVAVVAMT-DAASVNPDFPEYNWSEKTKSLLLSSFFWGYV 96

  Fly    79 LAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQ 142
            :.|.|||.|.:::|.|.::..|....|:|:.||......|||:..||:|:::|||| |.:|..|.
  Fly    97 ITQVPAGQLARKYGGKVMILSGLAICSILNILTPICAKIGGWQLVCALRVVEGLCQGVVFPSTHT 161

  Fly   143 HLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLG 207
            .|:.|.|..||..||..||:|...|.:|.:..:|:||:|.:|||.|.|.:.|:|.:|..::...|
  Fly   162 ILSQWAPPKERATLGTCAYSGNQFGTILMLATSGVIAASPIGWPSIFYISGGIGCVWSVVYFFFG 226

  Fly   208 ANKASDARFIGEAEKAYI----VGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLT 268
            |....:.:.|...||..|    ..::...:.:..:::..||...|||.....|:.:....:||..
  Fly   227 AGSPQECKSISAEEKKLIEMSQADEVSGGQEQPKEQLPTPWLSFFTSPAFLVLIVSHSVHNWGFW 291

  Fly   269 TMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIA 333
            |:.||:|:|:..:|..|:||||:.|:||::.|:.|.:|:..|:..|..:..:|.:|.||.:.||.
  Fly   292 TLLTEIPSYMKNILGKDIKSNALLSSLPYVCMFAMSFVFSSISAQLNNRNCISRSTSRKLFNSIG 356

  Fly   334 LWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNL 398
            ||.|...::.|..|...|..|.:||:..:||::.|..:|...|.||||||.||||.|:.:...|:
  Fly   357 LWIPMVTLVGLGYVNPDQSELAVVLLCFTVGMNGATYLGFNTNHIDLSPNFAGILMGITNGVANI 421

  Fly   399 MALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNE-SKESRRELEPE 462
            |:::.||:||.:||:.....||:|||.:|||....||.:::|:|.|..||||: ..:.||...|:
  Fly   422 MSIIAPLIVGFIVTNEHDPEQWRIVFFIAAGFYLVGNTLYVIFGKANVQPWNDPPAKPRRNSTPQ 486

  Fly   463 EKPFH 467
            .:..|
  Fly   487 VESQH 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	167/438 (38%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	143/387 (37%)
CG15096	NP_611376.1	2A0114euk	36..480	CDD:129972	170/444 (38%)
CG15096	NP_611376.1	MFS	40..464	CDD:119392	160/424 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442699
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.890