DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001009713.1	Gene:	Slc17a5 / 363103	RGDID:	1311388	Length:	495	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	138/485 - (28%)
Similarity:	243/485 - (50%)	Gaps:	47/485 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NDMEEIPKTVPRL-GLRHLQAG------------LLFYGLAANTVLQLNVSVAVVAM--TNETTS 51
            ||.||...:.|.| ..|.::|.            |.|.|......|::|:|||:|.|  :|.|.:
  Rat    11 NDDEESSDSTPLLPSARQIEAAPACCSARYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLT 75

  Fly    52 NN---------SDP---------PHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLF 98
            :|         |.|         ..|.|..|.:.:||.|:::|..:.|.|.||:..|.|.|.:|.
  Rat    76 DNRTSKECAEHSAPVKVHHNHTGKKYQWDAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLG 140

  Fly    99 WGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYT 162
            .|.||:::.:..|...... |..|...:|.|:||.: ||:|.:|...::|.|..||::|...:|.
  Rat   141 LGILGTAVFTLFTPLAADL-GVVALIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYA 204

  Fly   163 GFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVG 227
            |...|.|:::..:|:|. ..:.|..:.|....:|::|..||:.:.::.....:.|...||.|||.
  Rat   205 GAQLGTVISLPLSGIIC-YYMNWTYVFYLFGLVGIVWFILWMWIVSDTPETHKTISHYEKEYIVS 268

  Fly   228 DI--QRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNA 290
            .:  |.|.:|     .:||..|..|:|::|::.|..:.:|...|:.|.||||:..:|:.:::.|.
  Rat   269 SLKNQLSSQK-----VVPWVSILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQENG 328

  Fly   291 VFSALPFLLMWVMCYVYLIIADVLLRKKW-MSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTL 354
            ..||||:...| :|.:....|...||.|| .|..::|:.::.|.:..||..:::...:| ...:|
  Rat   329 FLSALPYFGCW-LCMIVCGQAADYLRVKWNFSTISVRRIFSLIGMVGPAVFLVAAGFIG-CDYSL 391

  Fly   355 VLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQ 419
            .:..:|:|..:...|:.|..:|.:|::|::||||.|:.::|..:..::.|::...|..|.:.: :
  Rat   392 AVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLGITNTFATIPGMIGPIIAKSLTPDNTIK-E 455

  Fly   420 WQIVFSLAAGVLFTGNVIFLIWGTAVTQPW 449
            ||.||.:||.:...|.:.|.::.....|.|
  Rat   456 WQTVFCIAAAINVFGAIFFTLFAKGEVQNW 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	130/451 (29%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	113/386 (29%)
Slc17a5	NP_001009713.1	2A0114euk	30..491	CDD:129972	131/466 (28%)
Slc17a5	NP_001009713.1	MFS	99..478	CDD:119392	113/388 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850