DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and CG3036

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	134/492 - (27%)
Similarity:	220/492 - (44%)	Gaps:	64/492 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMT--------------NETTSNNSDPP------- 57
            |..|.:...|...|...|..|::|:::|:|.|.              |.|.:|::..|
  Fly    16 LSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNSTAANSTASPDGVDVYE 80

  Fly    58 -HYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGGWK 121
             .:.|...:.:::|..::||..|.:.|.|.|.:..|.:.|.....|.:|||:.:|....:. .:.
  Fly    81 ERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHI-NYV 144

  Fly   122 AYCAIRLLQG-LCQVTWPCIHQHLANWCPTAERTR---------LGAFAYTGFDCGNVLAMYGAG 176
            ....:|::.| :...:||.||...|.|.|..||::         ||| |.|...||.::
  Fly   145 VLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSLGA-AITMPICGYLI------ 202

  Fly   177 MIASSSLGWPGISYSAAGLGLIWCGLWLLLGAN--------KASDARFIGEAEKAYIVGDIQRSE 233
                |..||..:.|....:||:|...|......        .|.:.|.|.||     :|  ..:.
  Fly   203 ----SVAGWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIEEA-----IG--TTTS 256

  Fly   234 RKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFL 298
            :|.|.  .:||..:..|..|:|::.......:|..|:..:|||::|.:|..|:|.|.:||:||:|
  Fly   257 KKRPS--HVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGLFSSLPYL 319

  Fly   299 LMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSV 363
            ..:||......:||.|.:|..:|.|..||.:|:.||..|..:|:..|.:|. ..|..:.:.:|::
  Fly   320 GKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGY-DATWSVTIFSLAL 383

  Fly   364 GVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAA 428
            ....|.|.|...|.:|::||..|.:.||.::.::....|:..:||.|.........|||||.:.|
  Fly   384 FAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQIVFWILA 448

  Fly   429 GVLFTGNVIFLIWGTAVTQPWNESKESRR--ELEPEE 463
            ....:..|:|.|.|:...||||...|..|  ::..||
  Fly   449 ATYISAAVVFAILGSGELQPWNNPPERVRISDVTQEE 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	129/472 (27%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	110/400 (28%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	130/479 (27%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	110/399 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960