DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and MFS17

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	137/504 - (27%)
Similarity:	239/504 - (47%)	Gaps:	71/504 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LQAGLLFY-----GLAANTVLQLNVSVAVVAM-TNETTSNN-------------SDPPHYNWSEE 64
            :.|.|:.|     |...:.:::.:::.|:||| .|:.::.|             :|       ::
  Fly    33 IPARLVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTD-------DQ 90

  Fly    65 K---KSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGGWKAYCAI 126
            |   ||.::||:||...|:|...|...:.||:|.|..|    |.|.:||.::.:.:.....|.|:
  Fly    91 KTIVKSVVISSFYWCYVLSQVVGGVATELFGTKCVFGW----SQLATALCSFMMPSAAQLHYIAV 151

  Fly   127 ---RLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPG 187
               |.:||... :|||.::..:..|.|..||:|..: ::.||..|..|.....|.|. |..|||.
  Fly   152 IVLRSIQGFASGLTWPAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYPLCGFIL-SEWGWPY 214

  Fly   188 ISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKMEIPWKGIFTSVP 252
            |.|:...|||.||.||.||..|...:...|.:.|..||..:::: |.....|:::||..||.|:|
  Fly   215 IFYTTGTLGLGWCILWYLLAFNTPREHPRITKDELNYIELNVKK-EVNSSVKVKVPWLQIFKSIP 278

  Fly   253 VYALLCARCADSWGLTTMQ---------TELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYL 308
            .:|:         .:||..         ...||::..|||.:.::|...|.:||:..::...::.
  Fly   279 AWAI---------AITTFGRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFC 334

  Fly   309 IIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVT---LSVGVSSAAT 370
            .|||.::..|.:.||.:||.:|:::...|..::..:     |....|.:|:|   ::|...:|:.
  Fly   335 YIADKIVFYKVLCLTNVRKVFTALSQIIPGVLIYCI-----GYIDNVYILLTVWFIAVIFITASY 394

  Fly   371 IGSELNTIDLSPN--HAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFT 433
            .|:..|.|||:||  |:..:.....:.....:.::||..|.:||......||:.||.::|.:...
  Fly   395 AGAMANIIDLAPNYGHSAAVLAFCQTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISIL 459

  Fly   434 GNVIFLIWGTAVTQPWNESKESRRELEPEEKPFHRAKLEIGTDNTDGNV 482
            ..:.:.::|||..|.||:......:.: |.|....||.::  |||.|.:
  Fly   460 TYLFYQLFGTAEIQTWNKGLPVNDDSD-EGKVLSTAKDDL--DNTGGPI 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	128/472 (27%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	112/403 (28%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	128/470 (27%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	120/453 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960