DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and MFS3

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	148/514 - (28%)
Similarity:	243/514 - (47%)	Gaps:	71/514 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EEIP-------KTVPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETT------------ 50
            :|:|       |.||   .|::.|.|...|:|....|::|:|||:|||.|.|.
  Fly     3 DEVPAKGSILGKLVP---ARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGG 64

  Fly    51 ------SNNS--------DPP-------------HYNWSEEKKSYILSSYYWGCALAQFPAGYLC 88
                  ||.|        :||             .::|||..:..:||.|:||..::|.|..::.
  Fly    65 HGSVILSNASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVA 129

  Fly    89 KRFGSKAVLFWG---TLGSSLLSALTTYGVYAGGWKAYCAIRLLQGL-CQVTWPCIHQHLANWCP 149
            :.|.:|.|:.:.   .:..:||:.:.|...|.|    ...:|:|:|: ...::|.:|..:|:|.|
  Fly   130 ENFSAKWVMLFSVAINVVCTLLTPVFTELHYGG----LILMRVLEGVGGGASFPAMHVMIASWAP 190

  Fly   150 TAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDA 214
            ..||..:....|.|...|..|::..|| :.|:..||..:.|....|..||..||::|..:..:..
  Fly   191 PTERMVMSTIIYVGTSAGTALSILLAG-VCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQ 254

  Fly   215 RFIGEAEKAYIVGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLS 279
            |||...|:..|...: .:|:|......:||..:|||||.:|:|.|....::|......|:|.|:.
  Fly   255 RFISLEERQMITSSL-GTEQKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMK 318

  Fly   280 GVLKLDMKSNAVFSALPF--LLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIML 342
            .|||.::.|||..||||:  ::::.:|...|:  |.|..|..::.|..|||.|||....|...:|
  Fly   319 QVLKFNVASNAALSALPYFPMIIFSICLGKLL--DSLQAKGKITTTVARKTATSICTLIPGVCLL 381

  Fly   343 SLVIVGEGQKTLVLVLVTLSVGVSSAATI--GSELNTIDLSPNHAGILAGLMSSFTNLMALLTPL 405
            .|..:|......|.|   :|||:.:..::  |...|.||::||.||.|..|.::...|..::.||
  Fly   382 VLCYIGCRHYEAVSV---MSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPL 443

  Fly   406 VVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRRELEPEEK 464
            .||.:.........|:|:|.:...:.....::|:..|:...||||::...:   :||.|
  Fly   444 FVGFVTKGNQNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAGTPK---DPEAK 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	138/479 (29%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	115/390 (29%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	139/480 (29%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	115/389 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960