DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	473	Identity:	145/473 - (30%)
Similarity:	229/473 - (48%)	Gaps:	52/473 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LRHLQAGLLFYGLAANTVL---QLNVSVAVVAMTNET-----------------------TSNNS 54
            |||   ||.|.....|..:   |:|:|.|:.||.|.|                       |...|
Mouse    32 LRH---GLAFILHLCNFSIYTQQMNLSFAITAMVNTTVASSQLNASTERPPTNSQDVWNETLQES 93

  Fly    55 DPPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVYAGG 119
            ..|.|:|:.|.:..:|||..:|..:|..|.||:...||:|.|:..|.|.||:|:........| |
Mouse    94 KAPVYDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPLAADA-G 157

  Fly   120 WKAYCAIRLLQGLCQV--------TWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAG 176
            ......:|::||:.||        .|       |.|.|..||::|...|.:|...|..|.:...|
Mouse   158 VALLIVLRVIQGMAQVMVLTGQYSLW-------AKWAPPQERSQLITIAASGSMLGTFLVLIAGG 215

  Fly   177 MIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKME 241
            :|. .:||||.|.|...|:|...|.||..|..:...:..||...|:.||...:.:.:..  ....
Mouse   216 LIC-QALGWPYIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCS--LGWS 277

  Fly   242 IPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYV 306
            :|.|.:..|:|::|::.:...:.|.|:|:....|||:|.||:.:::.:.:.|||||:...|...:
Mouse   278 LPIKAMVKSLPLWAIVVSYFCEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIIL 342

  Fly   307 YLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATI 371
            ..::||.||.:|.:.|.|:||.:|::.:.|.:.|:|.|..|...:.|.:..||..|| .:|....
Mouse   343 GGLLADFLLSRKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSV-FASLCDS 406

  Fly   372 GSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNV 436
            |:.:|.:|::|.:||.|.||:..|:.|...:.|.|.|..::..|:.. |:.||.|||.:...|.:
Mouse   407 GALINFLDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQDSEFG-WRNVFFLAAAIDVVGLL 470

  Fly   437 IFLIWGTAVTQPWNESKE 454
            .:||:..|..|.|  :||
Mouse   471 FYLIFSRAEVQDW--AKE 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	141/466 (30%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	121/390 (31%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	143/471 (30%)
		MFS	98..475	CDD:119392	121/389 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838716
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750