DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	136/474 - (28%)
Similarity:	226/474 - (47%)	Gaps:	44/474 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPH---------------------- 58
            ||:..|.::.:........::::|:|::||.|.|  .:.||.:
  Rat    25 LRYALALVMHFSNFTMITQRVSLSIAIIAMVNST--QHQDPANASAEGPVMNLLSNRSRGIKDFS 87

  Fly    59 -----YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALT----TYG 114
                 |.||.|.:..|.||..:|..|...|:|||...||:|.:|..|.|.||||:..|    .:|
  Rat    88 TRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFG 152

  Fly   115 VYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMI 178
            |.     ....||.:||:.| ::|.......|.|.|..||::|.:.|.:|...|:.:.:...|:|
  Rat   153 VI-----LVIVIRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLI 212

  Fly   179 ASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKMEIP 243
             |.:||||.|.|....:|.:.|.||..:..:.......|...||.||...:  :::....:..||
  Rat   213 -SQALGWPFIFYIFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSV--AQQSSSPRRSIP 274

  Fly   244 WKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYL 308
            .|.:...:|::|:.....:..|..|.:.|.||||:|.||.::::.:.|.|:|||:.......:..
  Rat   275 IKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSCTILGG 339

  Fly   309 IIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGS 373
            .:||.||.:..:||.|:||.::|:.|..|:...::|..| .......:||:.|..|.|:....|.
  Rat   340 QMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFV-TSSYIATIVLLILIPGTSNLCDSGF 403

  Fly   374 ELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIF 438
            .:||:|::|.:|..|.|:...|.....:::....|.|::..|: |.|:.||.|:|.|...|.:.:
  Rat   404 IINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQDSE-SGWRNVFFLSAAVNMFGLIFY 467

  Fly   439 LIWGTAVTQPWNESKESRR 457
            ||:|.|..|.|.:.:...|
  Rat   468 LIFGQAEIQNWAKERTLTR 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	132/464 (28%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	119/414 (29%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	129/452 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342553
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750