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Protein Alignment CG2003 and SLC17A5

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001369562.1	Gene:	SLC17A5 / 26503	HGNCID:	10933	Length:	533	Species:	Homo sapiens

Alignment Length:	458	Identity:	127/458 - (27%)
Similarity:	227/458 - (49%)	Gaps:	50/458 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NDMEEIPKTVPRL-------------GLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETT--- 50
            ||.||.....|.|             ..|:..|.|.|:|......|::|:|||:|.|.:..|
Human    11 NDGEESTDRTPLLPGAPRAEAAPVCCSARYNLAILAFFGFFIVYALRVNLSVALVDMVDSNTTLE 75

  Fly    51 ---SNNSDPPH--------------YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLF 98
               ::.:.|.|              |.|..|.:.:||.|:::|..:.|.|.||:..:.|.|.:|.
Human    76 DNRTSKACPEHSAPIKVHHNQTGKKYQWDAETQGWILGSFFYGYIITQIPGGYVASKIGGKMLLG 140

  Fly    99 WGTLGSSLLSALTTYGVYAG-GWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAY 161
            :|.||:::|:..|......| |  ....:|.|:||.: ||:|.:|...::|.|..||::|.:.:|
Human   141 FGILGTAVLTLFTPIAADLGVG--PLIVLRALEGLGEGVTFPAMHAMWSSWAPPLERSKLLSISY 203

  Fly   162 TGFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIV 226
            .|...|.|:::..:|:|. ..:.|..:.|....:|:.|..||:.|.::.....:.|...||.||:
Human   204 AGAQLGTVISLPLSGIIC-YYMNWTYVFYFFGTIGIFWFLLWIWLVSDTPQKHKRISHYEKEYIL 267

  Fly   227 GDI--QRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSN 289
            ..:  |.|.:|     .:||..|..|:|::|::.|..:.:|...|:.|.||||:..:|:.:::.|
Human   268 SSLRNQLSSQK-----SVPWVPILKSLPLWAIVVAHFSYNWTFYTLLTLLPTYMKEILRFNVQEN 327

  Fly   290 AVFSALPFLLMWVMCYVYLIIADVLLRKKW-MSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKT 353
            ...|:||:|..| :|.:....|...||.|| .|...:|:.::.|.:..||..:::...:| ...:
Human   328 GFLSSLPYLGSW-LCMILSGQAADNLRAKWNFSTLCVRRIFSLIGMIGPAVFLVAAGFIG-CDYS 390

  Fly   354 LVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRS 418
            |.:..:|:|..:....:.|..:|.:|::|::||||.|:.::|..:..::.|::...|.  |....
Human   391 LAVAFLTISTTLGGFCSSGFSINHLDIAPSYAGILLGITNTFATIPGMVGPVIAKSLT--PDAGV 453

  Fly   419 QWQ 421
            ||:
Human   454 QWR 456

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.