DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and SPAC1039.04

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_594995.1	Gene:	SPAC1039.04 / 2542960	PomBaseID:	SPAC1039.04	Length:	507	Species:	Schizosaccharomyces pombe

Alignment Length:	475	Identity:	98/475 - (20%)
Similarity:	175/475 - (36%)	Gaps:	105/475 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 KTVPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPHYNWSEEKKSYILSSY 73
            :.:|.|.|.:|          .|.:.:.|||.|      :|...:.|   ..:..::.:.::|.:
pombe    60 RILPLLALLYL----------FNALDKSNVSNA------KTNGMDKD---LGFVGDQYNIMISIF 105

  Fly    74 YWGCALAQFPAGYLCKRFGSKAVL--FWGTLGSSLL--SALTTYGVYAGGWKAYCAIRLLQGLCQ 134
            |....|..||..||.||||:..:|  |..:.|:..|  :|:..:|       ...|:|...|:.:
pombe   106 YIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFG-------GMMAVRWFLGMAE 163

  Fly   135 -VTWPCIHQHLANWCPTAERTRLGAFAYTGFDC----GNVLAMYGAGMIASSSL-GWPGISYSAA 193
             ...|.:..:|..:....|..|..|..|...:.    |.:|| ||...|....| ||..:.....
pombe   164 SAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLA-YGVFHIKGGKLQGWQYLFLIEG 227

  Fly   194 GLGLIWCG--LWLLLGANKASDARFIGEAEKAYIVGDIQR------SERKGPKK--------MEI 242
            |:..: |.  ::|:|..: ...|.|:.:.||......|:.      ||:...|:        :.|
pombe   228 GVTFL-CAIVIFLVLPVS-VETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSLTVFKHPIAI 290

  Fly   243 PW--KGIFTSVPVYALLCARCADSW--------GLTTMQTELPTYLSGVLKLDMKSNAVFSALPF 297
            .|  :.:...||:.::      ::|        |.:::.|.|.|....:      |.|:
pombe   291 LWLLEEMALGVPLNSI------NNWLPQIVAAMGFSSVNTNLMTVAPAI------SGAI------ 337

  Fly   298 LLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLS 362
               |::  |:..|:|.|..:..:.:..:..|.....::....||..:     |.......|:|..
pombe   338 ---WLL--VFAFISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHI-----GVSYFACFLMTAG 392

  Fly   363 VGVSSAATIGSELNTIDLSPNHA--GILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFS 425
            ...||..|.....|.   :||.:  .:...:.....|:|.|     |...:..|....::.....
pombe   393 AAASSVLTSTWYNNN---TPNESRRAVFTSVGVPLANVMGL-----VSANIFRPQDAPKYVPALG 449

  Fly   426 LAAGVLFTGNVIFLIWGTAV 445
            :.||  |.|..|.|:...:|
pombe   450 ITAG--FGGLGILLVASISV 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	94/461 (20%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	86/420 (20%)
SPAC1039.04	NP_594995.1	MFS	71..471	CDD:119392	94/454 (21%)
SPAC1039.04	NP_594995.1	2A0114	71..463	CDD:273326	93/448 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050