DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	535	Identity:	107/535 - (20%)
Similarity:	187/535 - (34%)	Gaps:	176/535 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNDMEEIPKTVPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPHYNWSEEK 65
            |.:.:::....|:...| |:..|.|..|....:|.:.:.:....::..:.....:..|.|  ..:
pombe    64 MQEAKDLEPLTPKQDKR-LRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHIN--SNQ 125

  Fly    66 KSYILSSYYWGCALAQFPAGYLCKRFG-SKAVLFWGTLGSSLLSALTTYGVY----AGGWKAYCA 125
            .:.|.:.:|.|..:.|.|...|.:||. ||.|        :..:||.|..::    |..:....|
pombe   126 YNDINTLFYVGFVIGQIPGHMLLQRFPVSKFV--------AASTALWTIIIFLHCAAYNFSGLMA 182

  Fly   126 IRLLQGLCQVT-WPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYG----AGMIASSSLGW 185
            :|...||.:.: .|.:...:..:.|.:|:..|..|.|        ::.||    ||.||.
pombe   183 LRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFY--------ISCYGCNIPAGFIAY----- 234

  Fly   186 PGISY-----SAAGLGLIWCG---LWLLLG-----ANKASDARFIGEAEKAYIVGDIQRS----- 232
             |:.|     |...|.:|..|   .:|.:|     .:..|.|||:.:.|:.|.|..::||
pombe   235 -GVQYAKNTISPWKLFMIIVGGITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGI 298

  Fly   233 ERKGPKKMEI------PWKGIFTSVPVYALLCARCAD--------------------------SW 265
            |.|..||.::      |...:||    :.:.|.:.::                          |.
pombe   299 ESKTFKKYQVIEALKDPVTWLFT----FHVFCNQLSNNLAYQQNLLFTSLNVSDLNSTLVGVASA 359

  Fly   266 GLTTMQTELPTYLSGVLK-------------------------LDMKSN---AVFSA----LPFL 298
            |...:...:.||:..|:|                         .|.|..   |:..|    :||:
pombe   360 GYNCVSAIIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIGELAAIIIASNFGIPFI 424

  Fly   299 --LMW---------------VMCYVYLIIADVLLRKKWMSLTTLRKTYTS-----IALWAPASIM 341
              |.|               ||..:...||:::..:.|.|....| .|.:     :..|:.:..:
pombe   425 ISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPR-YYPAWIVQIVIAWSVSPFV 488

  Fly   342 LSL---VIVGEGQKTLVLVLVTLSVGVSSAATIGSELN----------TIDLSPNH-AGILAGLM 392
            |.:   ::|...:|.|.|:                |.|          |||.|.|| :|.....|
pombe   489 LLIIRWILVRRNKKRLALL----------------EQNKEQYEKTWIETIDSSGNHVSGFYENSM 537

  Fly   393 SSFTNL--MALLTPL 405
            ...|:.  ::.:.||
pombe   538 LDLTDQENLSFIYPL 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	103/513 (20%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	99/478 (21%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	84/430 (20%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	82/424 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050