DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and SPBC1773.15

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_595130.1	Gene:	SPBC1773.15 / 2539757	PomBaseID:	SPBC1773.15	Length:	497	Species:	Schizosaccharomyces pombe

Alignment Length:	511	Identity:	99/511 - (19%)
Similarity:	182/511 - (35%)	Gaps:	139/511 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 VLQLNVSVAVVAMTNETTSN-----------NSDPPHYNWSEEKKSYILSSYYWGCALAQFPAGY 86
            |:.|...::.....:::|||           |.....|||       :.:|:|.|..:...|...
pombe    52 VMPLLCLISAFQYMDKSTSNYSSIMGIRTDLNMVGNQYNW-------VGTSFYLGFMVFSLPLST 109

  Fly    87 LCKRF-----GSKAVLFWGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLA 145
            |.::|     .|..::.||     :|..||   .....:.:|.|.|.|.|:.: |..|.....:|
pombe   110 LLQKFPLSKVTSAFIVAWG-----ILMTLT---CLVHSYASYIATRTLLGILESVITPAFVLFIA 166

  Fly   146 NWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLG----------------WPGISYSAAG 194
            .|....|:....||         ::|..|.|.:...|:.                | .|.:...|
pombe   167 QWYRKEEQFFRMAF---------LVAWNGLGGLIGGSMSYGLYKRELENNLTMSPW-RILFIITG 221

  Fly   195 LGLIWCGLWLLLG-ANKASDARFIGEAEKAYIVGDIQRSERKGPKKMEIPWKGIFT-SVPVYALL 257
            |..|..|:::.:. .::.|.|.|:.|.||..::           |:::....|:.: ....|.:|
pombe   222 LITIINGVFIFIHIPDEPSKAWFLSEKEKDLVL-----------KRLDTDHAGLGSKKFKKYQIL 275

  Fly   258 CARCADSWGLTTMQTELPTYLSGVLKLDMK-SNAVFSALPFLLMWVMCYVYLIIADVLLRKKWMS 321
            .| |.|          :..||...|::.:. .|...|....:::..:.||.   ...||    |:
pombe   276 EA-CRD----------VRMYLYFFLQIAVAIPNGGLSNFSSIMLKNLGYVK---GKALL----MN 322

  Fly   322 LTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATIGSELNT--------- 377
            :.|...::.::.|:.        :|.....:.:.:.||.|::.::|.:.|.....|
pombe   323 MPTSSISFAALTLFG--------LIPEFTNRRMDIALVGLAINLTSGSLIAFAKPTHAQLAGYWL 379

  Fly   378 IDLSP------------NHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQ-------IV 423
            ..:||            |.||....:..|..:::......:||......:|..::|       :.
pombe   380 FGISPIPYICILSCISSNSAGHTKKVFMSAVSMIGYCVGNMVGPQTFRSTQAPKYQGAKVSFVVC 444

  Fly   424 FSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRRELEPEEKPFHRAKLEIGTDNTD 479
            :.:|   :|   :|..|:...|       :|:||..|..|...:....|...|.||
pombe   445 YCVA---IF---IIIAIYAVNV-------RENRRRDEKNEYLSNELSEEDKKDLTD 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	91/486 (19%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	82/435 (19%)
SPBC1773.15	NP_595130.1	MFS	55..426	CDD:119392	82/432 (19%)
SPBC1773.15	NP_595130.1	2A0114	58..445	CDD:273326	83/448 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050