DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and SPCPB1C11.03

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_001342988.1	Gene:	SPCPB1C11.03 / 2539453	PomBaseID:	SPCPB1C11.03	Length:	570	Species:	Schizosaccharomyces pombe

Alignment Length:	486	Identity:	85/486 - (17%)
Similarity:	146/486 - (30%)	Gaps:	181/486 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNDMEEIPKTVPR----------------LGLRHLQAGLLFYG---LAANTVLQLNVSVAVVAMT 46
            |.|.:::....|:                ||...:   :||.|   |:.:|:|.|...|.:
pombe    77 MQDAKKLDPLTPKQESKLKWKLYIYLLLMLGFLDM---MLFIGKATLSYSTILGLFDDVHI---- 134

  Fly    47 NETTSNNSDPPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALT 111
               |||     .||       .:.:.:|.|..:.|||..|:.:.|.....:...|...|::..|.
pombe   135 ---TSN-----QYN-------NLNTLFYVGYIVGQFPGHYIMQTFPLGKFVGLVTFSWSVIVFLH 184

  Fly   112 TYGVYAGGWKAYCAIRLLQGLCQVTWPCI-------------HQHLANWCPTAERTRLGAFAYTG 163
            ......||   ..|:|...|.   |..|:             ||..|...|        .|..:.
pombe   185 CCAYNYGG---LIALRFFLGF---TESCLLPAMEATMGMFFTHQEQAFLQP--------VFWISC 235

  Fly   164 FDCG---NVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYI 225
            ..||   ..:| ||...:..|...|........|:.............:..|.|||:.:.||.|.
pombe   236 LSCGIPAGFIA-YGLEFVTKSIAPWKLFMIITGGITFFLSIFLFFYYPDNPSKARFLTDEEKLYT 299

  Fly   226 VGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNA 290
            :..:::|.|.|.:                                                  |.
pombe   300 IDRVRKSTRGGIE--------------------------------------------------NK 314

  Fly   291 VFSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLV 355
            :|                        ||...:..|:...|.:..:|..::|||..:.  .|:.|:
pombe   315 IF------------------------KKHQFIEALKDPITWLFTFAAFTLMLSNNLA--YQQNLI 353

  Fly   356 LVLVTLSVGVSSAATIGSELNTIDLSPNHAGI-LAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQ 419
            .                :.||..||:....|: |||    :..:.|::....:.::....:..:.
pombe   354 F----------------TSLNVSDLNSTLVGVALAG----YNTVSAIIATFAMYLIPNQSAYHAM 398

  Fly   420 WQIVFSLAAGVLFTGNVIFLIWGTAVTQPWN 450
            :.::.|:..|:.|            |..||:
pombe   399 FWMLPSITGGIAF------------VALPWS 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	80/448 (18%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	66/399 (17%)
SPCPB1C11.03	NP_001342988.1	UhpC	102..494	CDD:332119	82/461 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050