DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and SPCC417.10

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_588287.1	Gene:	SPCC417.10 / 2539419	PomBaseID:	SPCC417.10	Length:	508	Species:	Schizosaccharomyces pombe

Alignment Length:	561	Identity:	123/561 - (21%)
Similarity:	199/561 - (35%)	Gaps:	191/561 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DMEEI-PKTVPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSN-----------NSD 55
            |.:|| |:|..|| :|.:..          |:..:...|..:...::|:::           ..:
pombe    45 DYDEIDPETERRL-VRKIDC----------TIFPVMCLVYCIQFLDKTSNSYAVIMGLKEDLKME 98

  Fly    56 PPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFG-SKA----VLFWGTLGSSLLSALTTYGV 115
            ...|:||.       :::|.|..:.:|||..|.:||. ||.    ::.||     .|..:|:...
pombe    99 GQMYSWSG-------TAFYLGYLVFEFPASLLLQRFPLSKTLCVFLVIWG-----FLLCMTSVAN 151

  Fly   116 YAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFD-CGNVLAMYGA-GM 177
            |.|    :.|:|:|.|:.: ...|......|.|...:|: :|....:..|: .|.:|....| |:
pombe   152 YPG----FIALRVLLGMMESAASPGFILLTAQWYKRSEQ-QLRTSVWVAFNGLGQILGSCMAYGL 211

  Fly   178 IASSSL---GWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKK 239
            ...:||   ||.        |..|.||:.          |.|:|....|.:..:
pombe   212 AKRTSLPMRGWK--------LIFIICGVL----------AIFLGFVILAVVPDN----------- 247

  Fly   240 MEIPWKGIFTSVPVYALLCARC-ADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVM 303
               |:|..|.:.....|:..|. |:..|:.....:|  |......||:::            |:|
pombe   248 ---PFKAWFLTEEDRKLVVKRLRANKQGVGNNHFKL--YQFKETMLDIRT------------WIM 295

  Fly   304 CYVYLIIADV----------LLRKKWMSLTTLRKTYTSIALWAPASI----------MLSLVIVG 348
             :|..::.::          ||.|..|...||:    ::.:..||..          .|||.|
pombe   296 -FVSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQ----TLLMGLPAGACEFGGLIAFGFLSLFI-- 353

  Fly   349 EGQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTD 413
              .|.:||..:|..:     |.|||.|.:....|.  ..|||.      .:.:::|   |.::.
pombe   354 --HKRMVLATITTCI-----ALIGSCLLSFAGPPR--AQLAGY------YLLMVSP---GAMIV- 399

  Fly   414 PSQRSQWQIVFSLAAGVL--FTGNVIFLIW--------------------------------GTA 444
                 .:.|:.|.|:|..  .|..||:||.                                .|.
pombe   400 -----MFAIISSNASGYTKKVTVGVIYLIGYCVGNLIGPQTFKAADAPEYMPAKNTMVGCYAATL 459

  Fly   445 VTQP------WNESKESRRELEPEEKPFHRAKLEIGTDNTD 479
            ||.|      |.|:|. |.:|..|.|..||...|. .|.||
pombe   460 VTFPALYYVNWRENKR-RDQLAAEGKIEHRPNAEF-EDLTD 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	105/515 (20%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	94/416 (23%)
SPCC417.10	NP_588287.1	MFS	66..436	CDD:119392	97/463 (21%)
SPCC417.10	NP_588287.1	2A0114	71..468	CDD:273326	101/490 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050