Protein Alignment CG2003 and SLC17A8

DIOPT Version :9

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_647480.1
• Gene: SLC17A8 / 246213
• HGNCID: 20151
• Length: 589
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 138/498 - (27%)
• Similarity: 227/498 - (45%)
• Gaps: 42/498 - (8%)

  Fly    11 VPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPP-----HYNWSEEKKSYIL 70
            :|:..:..:.:||   |...:..::.|:.||:|.|.|.:|......|     .:||..|....|.
Human    72 LPKRYIIAIMSGL---GFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIH 133

  Fly    71 SSYYWGCALAQFPAGYLCKRFGSK-----AVLFWGTLGSSLLSALTT-YGVYAGGWKAYCAIRLL 129
            .|::||..:.|.|.|::..:|.:.     |:....||...:.||... ||       ....:|:|
Human   134 GSFFWGYIMTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYG-------CVMCVRIL 191

  Fly   130 QGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIASSSLGWPGISYSAA 193
            |||.: ||:|..|...:.|.|..||:||...::.|...|.|:||..||::. ..:||..:.|...
Human   192 QGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLV-QYIGWSSVFYIYG 255

  Fly   194 GLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDI-QRSERKGPKKMEIPWKGIFTSVPVYALL 257
            ..|:||...|||......:....|...||.||...| :.:......|...|||..|||:||||::
Human   256 MFGIIWYMFWLLQAYECPAAHPTISNEEKTYIETSIGEGANVVSLSKFSTPWKRFFTSLPVYAII 320

  Fly   258 CARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYVYLIIADVLLRKKWMSL 322
            .|....||....:....|.|...|....:....:.||:|.::|.::..:...:||.|..::.::.
Human   321 VANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRQILTT 385

  Fly   323 TTLRKTYTSIALWAPASIMLSLVIVG-EGQKTLVLVLVTLSVGVSSAATIGSELNTIDLSPNHAG 386
            |.:||..........|:::|   :|| ...|.:.:..:.|:||.|..|..|..:|.:|::|.:|.
Human   386 TAVRKIMNCGGFGMEATLLL---VVGFSHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYAS 447

  Fly   387 ILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTGNVIFLIWGTAVTQPW-- 449
            ||.|:.:....|..::.||:||.: |....|.:||.||.:||.|.::|.:.:.::.:...|.|
Human   448 ILMGISNGVGTLSGMVCPLIVGAM-TRHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQEWAD 511

  Fly   450 ----NESK-------ESRRELEPEEKPFHRAKLEIGTDNTDGN 481
                :|.|       |...|:|...:.|...|.::....|..|
Human   512 PENLSEEKCGIIDQDELAEEIELNHESFASPKKKMSYGATSQN 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	130/459 (28%)
		MFS	58..441	CDD:119392	115/391 (29%)
SLC17A8	NP_647480.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	40..61
		2A0114euk	75..513	CDD:129972	128/452 (28%)
		MFS	80..502	CDD:119392	126/436 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	559..589

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740