DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	493	Identity:	137/493 - (27%)
Similarity:	230/493 - (46%)	Gaps:	53/493 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MEEIPKTVPRLG---LRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPH------- 58
            |:|.|.|....|   ||:..|.::.:........::::|:|::||.|.|  .:.||.:
Mouse     1 MDEKPTTRKGSGFCSLRYALALIMHFSNFTMITQRVSLSIAIIAMVNST--QHQDPANASTEGPV 63

  Fly    59 --------------------YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLG 103
                                |.||.|.:..|.||..:|..|...|:|||...||:|.:|..|.|.
Mouse    64 MDLLSNQSRGIKDFSTRAAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLI 128

  Fly   104 SSLLSALT----TYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTG 163
            ||||:..|    .:||.     ....||.:||:.| :.|.......|.|.|..||::|.:.|.:|
Mouse   129 SSLLTLFTPLAADFGVI-----LVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSG 188

  Fly   164 FDCGNVLAMYG--AGMIASSSLGWPGISYSAAGL--GLIWCGLWLLLGANKASDARFIGEAEKAY 224
            .|.|:|..::.  .|.|   :|...|:::....|  |.:.|.||..:..:.......|...||.:
Mouse   189 EDVGSVWVLHHPLCGRI---NLTGTGLAFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEH 250

  Fly   225 IVGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSN 289
            |...:  :::....:..:|.|.:...:|::|:.....:..|..|.:.|.||||:|.||.::::.:
Mouse   251 ITSSV--AQQSSSPRRSVPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDS 313

  Fly   290 AVFSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTL 354
            .|.|:|||:.......:...:||.||.:..:||.|:||.::|:.|..|:...::|..| ......
Mouse   314 GVLSSLPFIAASSCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFV-TSSYIA 377

  Fly   355 VLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQ 419
            .:||:.|..|.|:....|..:||:|::|.:|..|.|:...|.....:::....|.|::..|: |.
Mouse   378 TIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQDSE-SG 441

  Fly   420 WQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRR 457
            |:.||.|:|.|...|.:.:||:|.|..|.|.:.:...|
Mouse   442 WRNVFFLSAAVNMFGLIFYLIFGQAEIQSWAKERTLTR 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	128/468 (27%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	115/418 (28%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	125/456 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838746
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750