DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	477	Identity:	126/477 - (26%)
Similarity:	223/477 - (46%)	Gaps:	45/477 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IPKTVPRLGLRHLQAGLLFYGLAANTVL---QLNVSVAVVAMTNETTSNNSDPPH---------- 58
            :||.||  |....:.||.......|.|:   ::.:::.:|||.|:|     :|||
  Rat     6 LPKKVP--GFCSFRYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKT-----EPPHLSNKSVAEML 63

  Fly    59 -------YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSALTTYGVY 116
                   ::||.:.:..||||.:.|..:.|.|.|||...:..|.::......||:||.|......
  Rat    64 DNVKNPVHSWSLDIQGLILSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIPPAAQ 128

  Fly   117 AGGWKAYCAIRLLQGLCQVTWPCIHQH--LANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIA 179
            .|. ......|:|||:.|.. ....||  ...|.|..||.||.:...:||..|..:|:..:|.|.
  Rat   129 VGA-ALVIVCRVLQGIAQGA-VSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFIC 191

  Fly   180 SSSLGWPGISYSAAGLGLIWCGL---WLLLGANKASDARFIGEAEKAYIVGDIQRSERKGPKKME 241
             ..||||.:.|.   .|::.|.|   |.:|..:..::..::..:||.||...:.:....|  :..
  Rat   192 -DLLGWPMVFYI---FGIVGCVLSLFWFILFFDDPNNHPYMSSSEKDYITSSLMQQVHSG--RQS 250

  Fly   242 IPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCYV 306
            :|.|.:..|:|::|::....|..|....:.|..||::|..|.::::.|.:.|:||:||.::...|
  Rat   251 LPIKAMLKSLPLWAIILNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIV 315

  Fly   307 YLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVLVLVTLSVGVSSAATI 371
            ...::|.||.:|..|:..:||.:|::.::.|...::.|:.:.....:.|:.| ||:....|.:..
  Rat   316 AGQMSDFLLSRKIFSVVAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFL-TLANSTLSFSFC 379

  Fly   372 GSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVT-DPSQRSQWQIVFSLAAGVLFTGN 435
            |..:|.:|::|.:.|.|..:.:.......|::..:.|:::. ||..  .|...|.|.||:..|..
  Rat   380 GQLINALDIAPRYYGFLKAVTALIGIFGGLISSTLAGLILNQDPEY--AWHKNFFLMAGINVTCL 442

  Fly   436 VIFLIWGTAVTQPW-NESKESR 456
            ..:|::.....|.| .|:|.:|
  Rat   443 AFYLLFAKGDIQDWAKETKTTR 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	119/459 (26%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	105/405 (26%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	125/475 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920