Protein Alignment CG2003 and VGlut

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: XP_317474.5
• Gene: VGlut / 1277956
• VectorBaseID: AGAMI1_010087
• Length: 597
• Species: Anopheles gambiae
• Alignment Length: 469
• Identity: 126/469 - (26%)
• Similarity: 207/469 - (44%)
• Gaps: 26/469 - (5%)

  Fly    34 LQLNVSVAVVAMTNETTSNNSDPPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLF 98
            ::.|:.:|.:...|.:..       |||:...:|.:.||::||..:.|.|.|:|...|.:..: |
Mosquito    97 MRCNMGMAKLQFENGSVK-------YNWTVAMESAVDSSFFWGYLVTQVPGGFLASMFPANRI-F 153

  Fly    99 WGTLGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYT 162
            ...:..|....|...|...........:|:||||.: ||:|..|.....|.|..||:||...|::
Mosquito   154 GTAIAISAFLNLLVPGAMMLHPTVVILVRVLQGLVEGVTYPACHGIWRFWAPPLERSRLATMAFS 218

  Fly   163 GFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVG 227
            |...|.|:.|..:| |.:.|:.|....|....:||||...||.|...|......|...|..||..
Mosquito   219 GSYAGVVIGMPMSG-ILTGSISWHAPFYFYGVMGLIWYCFWLWLSFEKPRQHPTISVKELKYIEK 282

  Fly   228 DIQRS-ERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAV 291
            .:..| :...|.....||:...||:||||::.|....||....:......||.......::...:
Mosquito   283 SLGESVQLPMPTIATTPWRHFLTSMPVYAIIVANFCRSWNFYLLVLYQSAYLKHSFDFRIEETGI 347

  Fly   292 FSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTL-V 355
            ..|||.|||.::.....::||.:.:...:|.|.:||.:.........   |..::|.....:: .
Mosquito   348 LGALPHLLMTIIVPFGGMLADHIRKSGLLSTTNVRKLFNCGGFGLEG---LFFLVVAHATSSMGA 409

  Fly   356 LVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQW 420
            :..:||.|..|..|..|..:|.:|::|.:|.||.|:.:....:..|:.|:.:..| |....:|.|
Mosquito   410 VTALTLGVAFSGFAISGYNVNHLDIAPRYASILMGMSNGIGTIAGLICPIAIDHL-TRGQPKSCW 473

  Fly   421 QIVFSLAAGVLFTGNVIFLIWGTAVTQPWNE-SKESRRELEP------EEKPFHRAKLEIGTDNT 478
            ..||::||.|...|...:.|:.:...|||.| :.|.:|..:|      :|..|:.|. :.|..:.
Mosquito   474 STVFTIAATVHLVGITFYGIFASGELQPWAEPTVEEQRAWDPVGSGYEKETTFNEAG-DGGAASP 537

  Fly   479 DGNVV--GLKLNCT 490
            .|.::  ..::|.|
Mosquito   538 SGGMMDPSAQINAT 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	112/410 (27%)
VGlut	XP_317474.5	None