Protein Alignment CG2003 and SLC17A3

DIOPT Version :10

• Sequence 1: NP_651903.2
• Gene: CG2003 / 43761
• FlyBaseID: FBgn0039886
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 142/492 - (28%)
• Similarity: 236/492 - (47%)
• Gaps: 62/492 - (12%)

  Fly     7 IPKTVPRLGLRHLQAGLLFYGLAANTVLQLNV--SVAVVAMTNETTS----NNSD---------- 55
            ||:.||.|........|:.:.....|:.| ||  ::.:|||.|.|:.    |:|.
Human    27 IPRKVPSLCSARYGIALVLHFCNFTTIAQ-NVIMNITMVAMVNSTSPQSQLNDSSEVLPVDSFGG 90

  Fly    56 -----------PPHYNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLS- 108
                       .|.|:||.:.:..|..:..:|..|...|:|||..|.|:|.|:......:|.|:
Human    91 LSKAPKSLPAKAPVYDWSPQIQGIIFGAVGYGGILTMAPSGYLAGRVGTKRVVGISLFATSFLTL 155

  Fly   109 ---ALTTYGVYAGGWKAYCAIRLLQGLCQ--------VTWPCIHQHLANWCPTAERTRLGAFAYT 162
               ..|.:|:.     .....|::|||.|        ..|       ..|.|..||:||.:.|.:
Human   156 CIPLATDFGIV-----LLIVTRIVQGLSQSSILGGQFAIW-------EKWGPPQERSRLCSIALS 208

  Fly   163 GFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVG 227
            |...|...|:...|.| |.:||||.:.|...|:|.:.|.||.::..:......:|..:||.||:.
Human   209 GMLLGCFTAILIGGFI-SETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWISTSEKEYIIS 272

  Fly   228 DIQRSERKGPKKMEIPWKGIFTSVPVYALLCARC-ADSWGLTTMQTELPTYLSGVLKLDMKSNAV 291
            .::  ::.|..|..:|.|.:..|:|::: :|..| :..|.::||...:|||:|.|..::::.|.:
Human   273 SLK--QQVGSSKQPLPIKAMLRSLPIWS-ICLGCFSHQWLVSTMVVYIPTYISSVYHVNIRDNGL 334

  Fly   292 FSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKTLVL 356
            .|||||::.||:..|...:||.||.||: .|.|:||..|.:.....:::::||..:..|..| ..
Human   335 LSALPFIVAWVIGMVGGYLADFLLTKKF-RLITVRKIATILGSLPSSALIVSLPYLNSGYIT-AT 397

  Fly   357 VLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVT-DPSQRSQW 420
            .|:|||.|:|:....|..:|.:|::|.::..|.|....|:::..::.|.|.|.|:: ||  ...|
Human   398 ALLTLSCGLSTLCQSGIYINVLDIAPRYSSFLMGASRGFSSIAPVIVPTVSGFLLSQDP--EFGW 460

  Fly   421 QIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRR 457
            :.||.|...|...|.:.:||:|.|..|.|.:.::..|
Human   461 RNVFFLLFAVNLLGLLFYLIFGEADVQEWAKERKLTR 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	MFS	21..442	CDD:475125	132/461 (29%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	132/460 (29%)