DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2003 and Slc17a3

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_598830.2	Gene:	Slc17a3 / 105355	MGIID:	2389216	Length:	498	Species:	Mus musculus

Alignment Length:	494	Identity:	138/494 - (27%)
Similarity:	226/494 - (45%)	Gaps:	61/494 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 IPKTVPRL---GLRHLQAGLLFYGLAAN-TVLQLN--VSVAVVAMTNETTSNNSDPPH------- 58
            :.|..|.|   .|..::.|:.|.....| |::..|  :|:.:|||.|    |...|||
Mouse    22 VNKKTPALKVPSLCSMRYGIAFVTHFCNFTLMAQNSIISITMVAMVN----NTDHPPHLNSSTEQ 82

  Fly    59 ----------------------YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGT 101
                                  ||||.:.:..|.||..:|..|.|.|.|||..:.|:|.|:....
Mouse    83 LPAGLSGDQHEASKHLPIKAPVYNWSPQTQGIIFSSVQYGMILMQGPGGYLAGKIGTKKVVGIAL 147

  Fly   102 LGSSLLSALTTYGVYAGGWKAYCAIRLLQGLCQVT--------WPCIHQHLANWCPTAERTRLGA 158
            ||||||:......... |...:.|.|.:|||.|.|        |       ..|.|..||:||..
Mouse   148 LGSSLLTLCIPLAANL-GLVFFLATRAVQGLMQGTGYGGQFALW-------QKWAPPNERSRLCT 204

  Fly   159 FAYTGFDCGNVLAMYGAGMIASSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKA 223
            .|.:|...| :..:...|.|.|.:||||.:.||..|.|::...||.:|..:......:|...|:.
Mouse   205 IALSGMTLG-IFTVLLVGGIISEALGWPFVFYSFGGGGVLCSLLWFILIYDDPVSHPWISGPERE 268

  Fly   224 YIVGDIQRSERKGPKKMEIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKS 288
            ||:..:  :::...::..:|.|.:..|:|::::........|.:.|.....|||:|.|.|::::.
Mouse   269 YILSSL--NQQFSSEEQPLPIKAMLKSLPLWSMCLCTMTHQWLVNTFIMYTPTYISSVFKVNIRD 331

  Fly   289 NAVFSALPFLLMWVMCYVYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVGEGQKT 353
            |...|:|||::.||:..:...:||.||.|.: .|.|:||..|.:....||:::.:|..:.....|
Mouse   332 NGFLSSLPFIVAWVLGILGGWLADFLLSKNF-RLITVRKFITLLGNAPPAALVAALPYIQSSYIT 395

  Fly   354 LVLVLVTLSVGVSSAATIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRS 418
            .::.| |:|.|:...:..|..:|.:|::|.:|..|.|......:..|:|.|:|.|..::..|:..
Mouse   396 TIIFL-TISCGLCPLSQAGIYINALDIAPRYASFLMGTSRGLAHSSAVLVPIVAGFFLSQDSEFG 459

  Fly   419 QWQIVFSLAAGVLFTGNVIFLIWGTAVTQPWNESKESRR 457
             |:..|.:...|...|.:|:|::|.|..|.|...::..|
Mouse   460 -WRNFFFVVFAVNLLGLIIYLVFGKADVQEWARERKLTR 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	132/472 (28%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	116/419 (28%)
Slc17a3	NP_598830.2	MFS_SLC17	42..482	CDD:340876	128/457 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47714
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750