DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2003 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_651903.2	Gene:	CG2003 / 43761	FlyBaseID:	FBgn0039886	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	517	Identity:	150/517 - (29%)
Similarity:	243/517 - (47%)	Gaps:	52/517 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MNDMEEIPKT------VPRLGLRHLQAGLLFYGLAANTVLQLNVSVAVVAMTNETTSNNSDPPH- 58
            :.:.:|:|..      :||   |::.|.|...|...:..::.|:.||||:|.|..|......|:
Zfish    43 LQEEKELPVVDCTCFGLPR---RYIIAILSGLGFCISFGIRCNLGVAVVSMVNNHTVYRDGKPYI 104

  Fly    59 ----YNWSEEKKSYILSSYYWGCALAQFPAGYLCKRFGSKAVLFWGTLGSSLLSAL--TTYGVYA 117
                ::|..|....|..|::||..:.|.|.|::|::|.:..|..:..:.:|:|:.:  |...::.
Zfish   105 VKAQFSWDPETVGMIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARMHF 169

  Fly   118 GGWKAYCAI--RLLQGLCQ-VTWPCIHQHLANWCPTAERTRLGAFAYTGFDCGNVLAMYGAGMIA 179
            |     |.|  |:||||.: |::|..|...|.|.|..||:||...|:.|...|.|:||..||::.
Zfish   170 G-----CVILVRILQGLVEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLV 229

  Fly   180 SSSLGWPGISYSAAGLGLIWCGLWLLLGANKASDARFIGEAEKAYIVGDIQRSERKG---P-KKM 240
            ..| ||..:.|.....|:.|...|:|:.....:....|...|:.||...|  .|..|   | .|.
Zfish   230 QYS-GWSSVFYVYGSFGVCWYLFWILVSYESPAAHPTITPEERKYIEDAI--GESAGLVNPLTKF 291

  Fly   241 EIPWKGIFTSVPVYALLCARCADSWGLTTMQTELPTYLSGVLKLDMKSNAVFSALPFLLMWVMCY 305
            ..||:..|||:||||::.|....||....:....|.|...|.|.::....:.||||.|:|.::..
Zfish   292 NTPWRQFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVMTIVVP 356

  Fly   306 VYLIIADVLLRKKWMSLTTLRKTYTSIALWAPASIMLSLVIVG-EGQKTLVLVLVTLSVGVSSAA 369
            :...:||.|.....|:.|.:||..........|:.:|   :|| ...|.:.:..:.|:||.|..|
Zfish   357 IGGQLADYLRTHNLMTTTNVRKLMNCGGFGLEATFLL---VVGFSHTKGVAISFLVLAVGFSGFA 418

  Fly   370 TIGSELNTIDLSPNHAGILAGLMSSFTNLMALLTPLVVGVLVTDPSQRSQWQIVFSLAAGVLFTG 434
            ..|..:|.:|::|.:|.||.|:.:....|..::.||:||.: |....|.:||.||.:|:.|.:.|
Zfish   419 ISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAM-TKNKTREEWQYVFLIASLVHYGG 482

  Fly   435 NVIFLIWGTAVTQPW----NESKE-----SRRELEPEEKPFHR-------AKLEIGTDNTDG 480
            .:.:.::.:...|||    |.|:|     ...||..|.:..:|       |.::.|..|..|
Zfish   483 VIFYGLFASGEKQPWAEPENTSEEKCGILGEDELADETEELYRSAGGGYGATMQSGDPNGAG 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2003	NP_651903.2	2A0114euk	23..456	CDD:129972	136/456 (30%)
CG2003	NP_651903.2	MFS	58..441	CDD:119392	119/397 (30%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582491
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740