Protein Alignment RhoGAP100F and syde2

DIOPT Version :9

• Sequence 1: NP_001163786.1
• Gene: RhoGAP100F / 43758
• FlyBaseID: FBgn0039883
• Length: 1866
• Species: Drosophila melanogaster
• Sequence 2: XP_017209238.1
• Gene: syde2 / 100333199
• ZFINID: ZDB-GENE-121116-6
• Length: 719
• Species: Danio rerio
• Alignment Length: 689
• Identity: 199/689 - (28%)
• Similarity: 303/689 - (43%)
• Gaps: 180/689 - (26%)

  Fly   700 LDRNMGLT-RPISALPVRSMSSQHIGGAGSIRSPSIRRMRQLLELSAGP----------ASPSGS 753
            |.|.:.:. .||:.:||.::.|:     ....||.:..|..|     ||          |..||:
Zfish     9 LSRKLSVKGNPINNVPVNNIQSE-----PRAHSPRVNGMADL-----GPSRLPPAGVTTALASGN 63

  Fly   754 IL-----------------------------STGGHQSPAPTPSATL------------------ 771
            ::                             |.||:.|...:|....
Zfish    64 VIWRYHLDSSVSTQHSFDKRRSNSAGVPKSASKGGYLSDGDSPELVAKSGKHTNSERKNCKTRDP 128

  Fly   772 ------PR-PHRQIDINPAEFAKYKLDKPIVDIGGISGMLWIHLLAGRGLRTAPEGAAGTATQGQ 829
                  |: |..::||:  .|..|...:....:..|||::.:|......|:         ..:..
Zfish   129 NGNGGSPKLPGTELDID--AFRSYSFTEQPKCLTYISGLMSLHFYGAEDLK---------LPRVD 182

  Fly   830 TRDLYCVIECDRVHKARTVVRSGDLQF-DWDESFELDLVGNKQLDVLVYSWD-PQHRHKLCYRGA 892
            :||:||.|:.|.|:||||.:.:....| |.|.:|.::|...:.|.::|:||: ...|:::|..|.
Zfish   183 SRDIYCAIQVDSVNKARTALLTCRTSFLDMDHTFNIELENAQHLKLVVFSWESTPRRNRVCCHGT 247

  Fly   893 ISLSSILRQSPLHQLALKVEPRGTIYIRMRHTDPLALYKRRGLPSLRAGYPTL--FGADLETVVN 955
            :.|..:.|.|..||||:::||||.||::      |:|.::| ..||...:|.:  ||.:...||.
Zfish   248 VVLPGLFRVSKTHQLAVRLEPRGMIYVK------LSLMEQR-QNSLDGDHPQMQVFGVEARHVVE 305

  Fly   956 RESKNAPGSAPVPIVLRRCVEEVERRGLDIIGLYRLCGSATKKRLLREAFERNSRAVELTPEHVP 1020
            ||:    ....||:::.:|:.|:||||..::|||||||||..|:.|||||||:|.:|||:..:.|
Zfish   306 REA----SGLMVPLLIEKCISEIERRGCQVVGLYRLCGSAAVKKELREAFERDSHSVELSESNYP 366

  Fly  1021 DINVITGVLKDYLRELPEPLFTRCLFQMTVDAL---------AVCLPDDPEGNAKLMLSILDCLP 1076
            |||||||||||||||||.||.|:.|::..::|:         |.|  ::...:::|.:|:||.||
Zfish   367 DINVITGVLKDYLRELPHPLITQQLYECVLEAMMKRPLLMGNAGC--ENTPADSQLTVSLLDILP 429

  Fly  1077 RANRATLVFLLDHLSLVVSNSERNKMSAQALATVMGPPLM--LHSASAQP----------GADID 1129
            ...:|:|..|||||..|.|:.|.|||..|.||...||.|:  ...||:|.          .:.:.
Zfish   430 DVEKASLKKLLDHLKRVASHHELNKMPCQNLAVCFGPVLLSQRQEASSQAKRVFIDSEELASALH 494

  Fly  1130 HAQPIAVLKYLLQIWPQPQAQHQQMAQHMGGAAGAMMGGLVTAGSMSNMAGVASGRRGESTGQRG 1194
            ..:.|.||.||||:||...|.                      |..|:...||      :|..|.
Zfish   495 FKKHIEVLHYLLQLWPVVDAH----------------------GKPSSPVPVA------ATAVRR 531

  Fly  1195 SKVSALPADRQQLLLQQQAQLMAAGNLLRSSTSVTNILSQGHPQLSATANNHLYQSVVGQLAQSH 1259
            .|      :|.|:|           ||  :...||.:|.....:|.:.:|.:         |...
Zfish   532 RK------ERPQVL-----------NL--TEVHVTGVLRPRAGRLDSPSNRY---------AGDW 568

  Fly  1260 RALQQAVQQPYQLGGSVGSAIPDPSPLPLPGTPSPGSSS 1298
            ...|.:..|...|..:....:|...||.......|.||:
Zfish   569 SGCQDSYLQQTSLEEADYDDVPSEEPLNTGQEDLPKSSA 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RhoGAP100F	NP_001163786.1	PDZ_signaling	177..260	CDD:238492
		C2	804..905	CDD:175973	28/102 (27%)
		RhoGAP_SYD1	946..1144	CDD:239844	95/218 (44%)
syde2	XP_017209238.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576385
Domainoid	1	1.000	165	1.000	Domainoid score	I3867
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004214
OrthoInspector	1	1.000	-	-		otm25019
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR46150
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2962
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.940